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Pleural Effusion                                                                       Pneumonia, Aspiration   1269



            Pleural Effusion
  VetBooks.ir  Cause               Appearance        Total Protein*  Cytologic Examination    Other Tests



            Pyothorax (septic exudate)  Cloudy, tomato soup   >4 g/dL  Degenerative neutrophils, intracellular and   Aerobic and anaerobic C&S
                                   appearance, malodor            extracellular bacteria, macrophages, RBCs
            Idiopathic chylothorax (modified   Milky white †  3 g/dL  Mature lymphocytes, few RBCs, few   Effusion and serum triglyceride
            transudate)                                           macrophages, few neutrophils  levels
            Right-sided (± left-sided in cats)   Clear  2 g/dL    Very few cells: RBCs, lymphocytes  Echocardiogram
            heart failure (modified transudate)
            Lymphoma (modified transudate   Clear, milky,   2-4 g/dL  Immature lymphoblasts, few mature   Thoracic radiographs, thoracic
            or nonseptic exudate)  serosanguineous                lymphocytes, few RBCs       ultrasound, aspirate/cytologic
                                                                                              examination of mass
            Thymoma (modified transudate or   Clear, milky,   2-4 g/dL  Mesothelial cells, mature lymphocytes,   Thoracic radiographs, thoracic
            nonseptic exudate)     serosanguineous                few RBCs, few macrophages   ultrasound, aspirate/cytologic
                                                                                              examination of mass
            Other neoplasia (e.g., carcinoma)   Clear, cloudy,   2-4 g/dL  Clumps of neoplastic cells  Thoracic radiographs, thoracic
            (modified transudate or nonseptic   serosanguineous, bloody                       ultrasound
            exudate)
            Hypoalbuminemia (pure   Clear, watery    <2.5 g/dL    Mononuclear cells (mesothelial cells,   Serum albumin, urine protein/
            transudate)                                           lymphocytes, macrophages)   creatinine ratio, bile acids
            FIP (cats) (nonseptic exudate)  Straw-colored, cloudy  >4 g/dL  Macrophages, lymphocytes, RBCs, fibrin  FIP PCR on fluid
           *To convert from g/dL to mg/mL, multiply g/dL by 10.
           † Occasionally translucent; definitive diagnosis via triglyceride concentration, which is higher in chylous effusions than in blood.
           C&S, Culture and susceptibility; FIP, feline infectious peritonitis; PCR, polymerase chain reaction; RBCs, red blood cells.  Differentials, Lists,   and Mnemonics
           Modified with permission from King L: Textbook of respiratory disease in dogs and cats, St. Louis, 2004, Saunders, p 16.





            Pneumonia, Aspiration



             Conditions Predisposing an Animal to Aspiration of Stomach Contents
             Impairment of Protective Airway Reflexes  Large Volumes of Intragastric Food/Fluid  Impaired Function of Gastroesophageal
               Coma                              Delayed gastric emptying:        Sphincter
               Head trauma                          Ileus                           Presence of a nasogastric feeding tube
               Metabolic derangements               Bowel obstruction               Achalasia
               Central depressant medications (sedation,   Pain                     Esophageal obstruction
                 general anesthesia)                Anxiety                         Abnormalities of esophageal function:
               Muscle relaxants                     Opioid medication                 Megaesophagus
               Seizures                             Peristaltic abnormalities         Reflux esophagitis
               Airway trauma                        Pregnancy                         Myasthenia gravis
               Laryngeal dysfunction (including laryngeal   Obesity                   Esophageal dysmotility
                 paralysis before and after surgical treatment)  Overfeeding by enteral tube
               Pharyngeal dysfunction            Recent meal (before emergency anesthesia/
               General anesthesia                   surgery)
           Modified from King L: Textbook of respiratory disease in dogs and cats, St. Louis, 2004, Saunders, p 423.




















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