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Adenocarcinoma of the Anal Sacs   1399



            Adenocarcinoma of the Anal Sacs
  VetBooks.ir                               Histologic diagnosis of anal sac adenocarcinoma





                                             • Thoracic and abdominal imaging
                                             • Serum biochemical profile +/- ionized calcium


                                                     Is patient hypercalcemic?  Yes  Treat hypercalcemia
                                                              No
                                        Evidence of distant metastasis beyond regional lymph nodes?
                                             No                                    Yes
                              Is surgery alone sufficient for complete      Treat palliatively with
                                resection of primary tumor as well  No       surgery, radiation,
                               as functional and cosmetic outcome?        chemotherapy as indicated;
                                                                           the efficacy of adjuvant
                                             Yes                           chemotherapy remains
                                                                               poorly defined
                                   Wide surgical excision with
                                 evaluation of histologic margins


                                     Complete resection?  No  Combine radiation therapy and
                                                             surgery to treat the primary tumor
                                             Yes

                                            Evidence of sublumbar  Yes  Consider surgery and/or radiation
                                              lymphadenopathy?         therapy for regional lymph nodes
                                                     No
                                               Consider chemotherapy for the treatment
                                                    of micrometastatic disease
           UPDATED AND EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
           ORIGINALLY WRITTEN BY: Elizabeth A. McNiel, DVM, PhD, DACVIM, DACVR











                                                                                                                      Clinical   Algorithms





















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