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Icterus: Management 1430.e1



            Icterus: Management
  VetBooks.ir                                               Icterus







                 • Moderate to severe anemia                                     • Mild or no anemia
                 • Normal to slight increase in alanine amino-                   • No red blood cell regeneration
                   transferase and alkaline phosphatase activity                 • Moderate to severe increase in
                                                                                   alanine aminotransferase and
                                                                                   alkaline phosphatase activity


                        Evaluation for hemolysis
                                                     Abdominal ultrasonography




                  Changes in hepatic           Gallbladder or              Abdominal          Mass in gallbladder,
                 parenchyma suggestive        bile duct distention          effusion           common bile duct,
                 of primary liver disease                                                       or duodenum

             • Consider toxins (see
              Hepatotoxins, p. 1231)    Hepatobiliary  Repeat abdominal  Abdominocentesis         Exploratory
             • Consider leptospirosis   scintigraphy  ultrasound exam(s)  with cytology, culture,  surgery
             • Consider biopsy (perform                                  bilirubin analysis
               coagulation profile first) or
               aspirate for histologic
               examination, cytologic
               evaluation, and bacterial culture                         Bacteria or toxic/  • Gallbladder mass:
                                                                          degenerative        cholecystectomy
                                                                        polymorphonuclear   • Bile duct mass: CCD
                                                                          leukocytes or     • Duodenal mass: resect
                                                                        bilirubin ≥2 × serum    and CCD; or decompress
                   No obstruction                                            level            (i.e., tube drainage) to
                                           Obstruction
                                                                                              stabilize before resection

                 Medical treatment
                  Monitor or biopsy   Evidence of pancreatitis?           Exploratory
                Explore if deteriorates                                     surgery
                                    No                Yes


                    Exploratory surgery               Management    • Necrotizing cholecystitis:
                    • Bile duct obstructed beyond cystic  of pancreatitis  cholecystectomy
                      duct: CCD                                     • Ruptured gallbladder: repair
                    • Cholecystoliths: cholecystectomy               or cholecystectomy
                    • Choledocholiths: flush or remove and          • Ruptured bile duct beyond                       Clinical
                      cholecystectomy ± choledochotomy               cystic duct: ligate and CCD                       Algorithms
                    • Cholelith at sphincter: sphincterotomy        • Torn hepatic duct: ligate
                      or sphincteroplasty
                    • Bile duct mass: CCD
                    • Duodenal mass: resection and CCD
                    • Pancreatic mass: CCD

               CCD, Cholecystoduodenostomy.
               (Modified from Slatter DH: Textbook of small animal surgery, ed 3, St. Louis, 2003, Saunders.)










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