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Soft-Tissue Sarcoma: Diagnostic and Therapeutic Approach 1451

Soft-Tissue Sarcoma: Diagnostic and Therapeutic Approach
VetBooks.ir Mass/tumor: Is FNA cytology No Pursue further diagnostics

consistent with sarcoma?
Yes based on the type of lesion

• Are distant metastases detected? Yes Consider chemotherapy,
• Thoracic radiographs, abdominal ultrasound palliative radiotherapy, or
palliative care
No
Can the tumor and a wide margin be easily
removed with surgery?
Yes No

Excisional biopsy/surgery If complete excision is not • Incisional biopsy to confirm sarcoma
possible: • Histologic evaluation and grading before
• Excisional biopsy/surgery or treatment
• Consider radiation before
surgery
Was surgical excision complete?
Yes No

Histologic grade Histologic grade

Grades 1 and 2 Grade 3 Grades 1 and 2 Grade 3

Routine monitoring Adjuvant chemotherapy • Radiation therapy, or • Local control (radiation
• Repeat excision, or therapy or repeat excision)
FNA, Fine-needle aspiration. • Metronomic chemotherapy and adjuvant chemotherapy

EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
ORIGINALLY WRITTEN BY: John Farrelly, DVM, MS, DACVIM, DACVR

Clinical Algorithms

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