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232.e4  Cystadenoma, Hepatobiliary


           Differential Diagnosis                 patient  (e.g.,  patients  with  comorbid   total solids, and decreasing body temperature
           Congenital or acquired hepatic cysts, hepatic   conditions in which cystadenoma is an   can be suggestive of hemorrhage in the immedi-
  VetBooks.ir  cystadenocarcinoma),  metastatic  hepatic  •  Enteral  feeding  should  be  considered   Client Education
                                                  incidental finding).
                                                                                 ate postoperative period.
           abscess, malignant hepatobiliary tumors (e.g.,
           neoplasia
                                                postoperatively in patients that are anorectic
           Initial Database                     (esophagostomy or gastrostomy tubes) (pp.   Percutaneous cyst drainage may be palliative
                                                1106 and 1109).
                                                                                 in selected cases; however, given the excellent
           •  Serum  biochemical  profile,  CBC,  and                            prognosis associated with complete excision,
            urinalysis are generally unremarkable.  Possible Complications       surgical intervention is usually advised.
           •  Abdominal  radiographs  may  prove  useful   Hemorrhage  and  bile  leakage  with  resultant
            with large cysts that displace surrounding   bile peritonitis are potential postoperative   SUGGESTED READING
            structures.                       complications.                     Nyland TG, et al: Ultrasonographic evaluation of
           •  Ultrasonography  is  the  diagnostic  test  of                       biliary cystadenomas in cats. Vet Radiol Ultrasound
            choice. It reveals fluid-filled mass(es) with   Recommended Monitoring  40:300-306, 1999.
            internal septa, with variable tissue compo-  Follow-up hepatic ultrasound to monitor for
            nents. The mass can appear hypoechoic or   recurrence in cases with incomplete excision or   ADDITIONAL SUGGESTED
            anechoic due to the cystic nature of the   in patients that do not undergo surgery  READINGS
            lesion.                                                              Balkman C: Hepatobiliary neoplasia in dogs and cats.
           •  Aspiration  of  the  cystic  fluid  yields  an    PROGNOSIS & OUTCOME  Vet Clin North Am Small Anim Pract 39:617-625,
            acellular fluid with a low total protein                               2009.
            concentration (<2.0 g/dL).        •  Hepatobiliary  cystadenomas  are  usually   Larson MM: Ultrasound imaging of the hepatobiliary
           •  If  surgical  excision  or  biopsy  is  planned,   incidental findings, and most do not cause   system and pancreas. Vet Clin North Am Small
            preoperative coagulation profile is indicated   clinical signs.        Anim Pract 46:453-480, 2016.
            (p. 1325).                        •  Complete tumor excision warrants an excel-  Moon SJ, et al: Biliary cystadenoma in a Maltese
                                                lent prognosis.                    dog: clinical and diagnostic findings. J Vet Med
           Advanced or Confirmatory Testing   •  Given the slow-growing nature of the tumor,   73:1677-1679, 2011.
           •  Advanced imaging (CT or MRI) is generally   surgical debulking of nonresectable lesions   Trout NJ, et al: Surgical treatment of hepatobiliary
                                                                                   cystadenoma in cats: five cases (1988-1993). J Am
            not indicated.                      may provide long-term palliation.  Vet Med Assoc 206:505-507, 1995.
           •  Histopathologic evaluation is required for a   •  Hepatobiliary cystadenomas are not known
            definitive diagnosis; a presumptive diagnosis   to have malignant potential in veterinary   RELATED CLIENT EDUCATION
            may be made by a skilled ultrasonographer.  medicine, but malignant transformation has
                                                been reported in humans with hepatobiliary   SHEETS
            TREATMENT                           cystadenoma.                     Consent to Perform Abdominal Ultrasound
                                                                                 Consent to Perform Exploratory Laparotomy
           Treatment Overview                  PEARLS & CONSIDERATIONS           Consent to Perform General Anesthesia
           Complete surgical excision can be curative                            Consent to Perform Radiography
           and is always advised if there are clinical signs.   Comments
           Animals with small lesions, a typical ultraso-  Histopathologic evaluation is ideal for all cystic   AUTHOR: Fredrick S. Pike, DVM, DACVS
           nographic appearance, and no clinical signs   hepatic lesions to rule out malignancy.  EDITOR: Keith P. Richter, DVM, MSEL, DACVIM
           can be monitored instead by ultrasonography.
                                              Technician Tips
           Acute and Chronic Treatment        The most common perioperative complication
           •  Surgical  removal  to  prevent  progressive   associated with liver surgery is hemorrhage.
            enlargement and associated clinical signs  Compatible blood products should be available
            ○   The decision to excise the mass must   before surgery. Increasing heart rate, decreasing
              be weighed against the condition of the   blood pressure, decreasing packed cell volume/




























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