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Ectopic Ureter   283


               dorsolateral location but then tunnels   with  the  kidneys,  ureter  (if  visible),  and   correction  or laser  ablation by transurethral
               through the submucosa of the bladder   bladder                     cystoscopy.
  VetBooks.ir  location. Amenable to cystoscopic laser    Advanced or Confirmatory Testing  Acute General Treatment   Diseases and   Disorders
               and opens distal to the normal trigone
                                               Abdominal ultrasound (may be normal):
               ablation
                                                                                  •  Appropriate treatment of concurrent urinary
           HISTORY, CHIEF COMPLAINT            •  Hydroureter                       tract infection (if present) is important before
                                               •  Hydronephrosis
                                                                                    surgery.
           •  Urinary  incontinence,  intermittent  or   •  Ureterocele           •  Surgical technique used depends on the loca-
             continuous                        •  May  see  abnormal  location  of  ureteral    tion and morphology of the ectopic ureter.
           •  Recurrent  urinary  tract  infections  (typi-  orifice                Surgical techniques commonly performed:
             cally  causing  pollakiuria,  stranguria,  and/  •  Evidence of cystitis if secondary urinary tract   ○   Ureteral reimplantation with ligation
             or hematuria)                      infection                             of  the  distal  ureter  (extramural  ectopic
                                               Excretory urography (EU) with survey radio-  ureters)
           PHYSICAL EXAM FINDINGS              graphs (p. 1101):                    ○   Neoureterostomy  and  urethra-trigone
           •  Moist or urine-stained hair in the perivulvar/  •  Identify location of ureteral opening distal   reconstruction (intramural ectopic ureters)
             preputial region                   to the trigone of the bladder       ○   Nephroureterectomy: removal of a non-
           •  Urinary incontinence may be noted during   •  Ureteral dilation (>0.09 times the length of   functional kidney and associated ureter;
             physical exam.                     the L2 vertebrae)                     considered a salvage procedure. Important
           •  Dermatitis due to urine scalding  ○   Most commonly associated with intramu-  to determine  renal function  in the
           •  Small or moderately sized bladder on palpa-  ral ureters that open into the urethra or   contralateral kidney is normal
             tion (typically small)               vagina                          •  Cystoscopic-guided laser ablation
           •  Vulvovaginal stricture or persistent hymen   ○   Due  to  intermittent  or  partial  urinary   ○   Laser ablation of the wall between the
             palpated on digital vaginal exam     obstruction and/or secondary to a urinary   urethral lumen and the intramural ureteral
           •  Vulvovaginitis                      tract infection                     lumen is practical only for patients with
                                               •  Lateral, ventrodorsal, and oblique views are   intramural ectopic ureters.
           Etiology and Pathophysiology         necessary to identify the distal segment of   ○   Can be an effective, minimally invasive
           •  Ectopic ureters are the result of dysembryo-  nondilated ureters.       technique for correction of intramural
             genesis of the ureteral bud of the mesonephric   •  Inability  to  consistently  identify  ectopic   ectopic ureters
             duct.                              ureter may be due to ureteral peristalsis, poor   ○   Performed using a holmium:YAG or diode
           •  The deviation of the ureteral bud from the   renal excretion of contrast, or superimposi-  laser
             normal position determines the location of   tion of other structures.  ○   Limited availability
             the ectopic opening.              •  Diagnostic accuracy improves if combined
                                                with pneumocystography.           Chronic Treatment
            DIAGNOSIS                          Contrast-enhanced CT scan (EU with CT):  Management of concurrent urethral sphincter
                                               •  Sensitive and specific method for diagnosis   mechanism incompetence, if present (p. 1011)
           Diagnostic Overview                  and characterization of ectopic ureters (e.g.,
           Ectopic ureters should be suspected in   exact location of ureteral orifice, identifying   Possible Complications
           any young dog with urinary incontinence.   multiple openings)          •  Hydroureter  and  hydronephrosis  due  to
           Confirmation requires advanced imaging   Transurethral cystoscopy (p. 1085):  obstruction postoperatively
           (abdominal ultrasound, excretory urography,   •  Direct visualization of the lower urinary tract   •  Persistent  urinary  incontinence:  most
           contrast-enhanced  CT,  or  transurethral     using a rigid or flexible endoscope  common complication after surgical repair
           cystoscopy).                        •  Identification of ectopic ureteral openings,   of ectopic ureters (40%-70% of patients)
                                                but may be difficult to confirm intramural   •  Recurrent urinary tract infections
           Differential Diagnosis               nature of ureter with cystoscopy alone (CT
           Differential diagnosis for urinary incontinence:  or fluoroscopy may be useful for this)  Recommended Monitoring
           •  Ureterocele                      •  Allows for identification of other congenital   Routine monitoring for urinary tract infections
           •  Pelvic bladder                    structural abnormalities of the lower urinary
           •  Urge incontinence (e.g., urinary tract infec-  tract involving the bladder, vagina, vestibule,    PROGNOSIS & OUTCOME
             tion, urolithiasis)                and urethra
           •  Urethral sphincter mechanism incompetence  •  Commonly paired with CT or performed   •  Prognosis with surgical repair or laser abla-
           •  Vaginal abnormality (e.g., vaginal stricture)  alone by a skilled cystoscopist  tion of ectopic ureter(s) is good if there is
           •  Neurologic disorders             Urodynamic evaluation:               no evidence of renal dysfunction  before
           •  Congenital  urethral  incompetence  or   •  Determination of the urethral pressure profile   surgery.
             hypoplasia                         may be useful in gaining information regard-  •  Prognosis for return of urinary continence
                                                ing function of the urethra in patients with   without specific therapy for urethral sphincter
           Initial Database                     urinary incontinence.               incompetence is poor, with up to 70% of
           Urinalysis (may be normal):         •  Used to help predict continued postoperative   dogs remaining incontinent postoperatively.
           •  Pyuria                            urinary incontinence in patients with ectopic   Most dogs will improve with medical man-
           •  Hematuria                         ureter                              agement for urethral sphincter mechanism
           •  Bacteriuria                      •  Limited availability              incompetence.
           Abdominal radiographs (often normal):
           •  Provide  information  regarding  the  size,    TREATMENT             PEARLS & CONSIDERATIONS
             shape, and location of the kidneys and
             bladder                           Treatment Overview                 Comments
           •  Small bladder size               The treatment goal for patients with ectopic   •  Ectopic ureter(s) should be suspected in any
           •  Pelvic bladder                   ureters consists of correcting the abnormal   young dog with urinary incontinence.
           •  Mainly used to rule out cystolithiasis and   urethral  orifice  to  resolve  or  reduce  urinary   •  Although surgery is often successful for surgi-
             identify structural abnormalities associated   incontinence.  This  requires  open  surgical   cal correction of ectopic ureters, 40%-70%

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