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284   Edema, Subcutaneous


            of  dogs  will  still  have  urinary  inconti-  and fluid overload may indicate possible urinary   SUGGESTED READING
            nence after surgical correction due to   tract obstruction.          Davidson AP, et al: Diagnosis and management of
  VetBooks.ir  Technician Tips                Client Education                   AUTHOR: Laura A. Nafe, DVM, MS, DACVIM
            concurrent urethral sphincter mechanism
                                                                                   urinary ectopia. Vet Clin North Am Small Anim
            incompetence.
                                                                                   Pract 44:343-353, 2014.
                                              Understanding that a large percentage of dogs
           Immediate postoperative monitoring should   with ectopic ureters continue to have urinary   EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
                                              incontinence after repair of the ectopic ureter(s)
           focus on urine production and fluid volume   is important when discussing surgery and
           status because signs of reduced urine production   postoperative expectations with clients.




            Edema, Subcutaneous



            BASIC INFORMATION                   are consistently well-defined, even in obese   •  Increased vascular permeability
                                                animals.  With  edema,  these  areas  are  less   ○   Allergic response (histamine release)
           Definition                           defined and overlying skin has a thickened,   ○   Acute inflammation
           Local or generalized swelling from excessive   jelly-like appearance.   ○   Burn injury
           fluid accumulation in the interstitial tissue   •  Edema tends to accumulate where gravity   ○   Envenomation
           spaces under the skin. Normally, only a small   draws  it, where lymphatic  obstruction or   Normal volume of interstitial fluid not reab-
           amount of fluid leaks from vessels into the   insufficiency is greatest, or a combination   sorbed by the lymphatic system:
           interstitium, and it is removed by lymphatic   of both. The pattern of edema distribution   •  Lymphatic obstruction (usually localized)
           vessels.                             varies.                            ○   Neoplasia
                                              •  Additional  physical  abnormalities  depend   ○   Inflammation
           Synonyms                             on underlying cause of edema.      ○   Trauma
           Peripheral edema (edema of the head, neck,                              ○   Congenital (lymphedema)
           torso,  and/or  limbs),  anasarca  (generalized,   Etiology and Pathophysiology
           massive subcutaneous [SQ] edema)   More fluid leaves the capillaries than enters:   DIAGNOSIS
                                              •  Increased vascular hydrostatic pressure
           Epidemiology                         ○   Right-sided CHF              Diagnostic Overview
           SPECIES, AGE, SEX                    ○   Impaired venous flow (e.g., mediastinal   •  SQ  edema  is  identified  on  physical  exam
           Dogs and cats: any age, either sex     or abdominal mass)               (readily if severe, with difficulty if mild).
                                                ○   Iatrogenic fluid overload    •  Diffuse edema, or edema in disparate loca-
           RISK FACTORS                         ○   Excessive  fluid  retention  (e.g.,  anuric   tions, suggests systemic disturbance. Regional
           Severe hypoproteinemia, right-sided congestive   kidney failure)        edema (e.g., head/neck, single limb) suggests
           heart failure (CHF), inflammation, vasculitis,   •  Decreased plasma oncotic pressure  regional disease.
           extensive trauma or heat, lymphatic malforma-  ○   Hypoalbuminemia:  increased  loss  or   •  Acute edema is more likely related to causes
           tion, acquired venous or lymphatic obstruction   decreased production (p. 1239)  such as allergy, envenomation, or thermal
           (e.g., tumor, granuloma)
           Clinical Presentation
           HISTORY, CHIEF COMPLAINT
           Regional swelling (e.g., one limb, both hind
           limbs, head) or a diffusely swollen appearance,
           most  commonly  in  dependent  areas  (e.g.,
           sternum, distal limbs, scrotum)
           PHYSICAL EXAM FINDINGS
           •  Local or diffuse thickening of SQ tissues
            ○   Most commonly, edema pits. Digital pres-
              sure exerted on edematous skin may leave
              a depression (i.e., pit) for several seconds
              after the pressure is released, when fluid
              accumulation  is  interstitial  rather  than
              intracellular.
            ○   Although uncommon, swelling may
              be painful or warm if associated with
              infection.
            ○   Sometimes associated with ascites (e.g.,
              hypoalbuminemia, right-sided CHF)
           •  The  hock  with  its  lateral  saphenous  vein,
            the gastrocnemius tendons, and the bony   EDEMA, SUBCUTANEOUS  Subcutaneous edema in the tarsal region of a dog. In this image, the clinician
            prominence of the mandible are useful to   just removed her index finger after applying digital pressure for several seconds, revealing the depression or
            evaluate for SQ edema because these areas   pit (arrows) that characterizes pitting edema.

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