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296   Entropion/Ectropion


            CHF or severe neurologic complications are   and a new murmur, particularly a diastolic   cefazolin 22 mg/kg IV) before the start of the
            not present initially.              murmur.  Diastolic  murmurs  are  typically   •  Year-round  use  of  ectoparastie  prevention
                                                                                   procedure.
           •  Recurrence or treatment failure is likely with
                                                soft, blowing, decrescendo, and best heard
  VetBooks.ir  inadequate duration of therapy, inappropriate   •  Identification of an independently oscillating   Technician Tips
                                                at the left heart base.
                                                                                   should reduce the risk of bartonellosis.
            antibiotic selection, or owner nonadherence
            to prescribed treatment.
           •  Despite  optimal  therapy  and  monitoring,   mass  (vegetation),  along  with  suggestive   •  Animals  with  IE  are  usually  very  ill,  and
                                                clinical signs, is consistent with IE.
            cure rates for IE do not appear promising   •  Culture-negative  IE  is  common  in  veteri-  symptoms of sepsis are common.
            for dogs, and CHF or other serious or fatal   nary medicine, often warranting empirical   •  IE is an important cause of diastolic heart
            complications are common.           antibiotic therapy.                murmur.
            PEARLS & CONSIDERATIONS           Prevention                         SUGGESTED READING
                                              •  Animals with SAS, implanted cardiac devices   MacDonald K: Infective endocarditis in dogs: diag-
           Comments                             (e.g., transvenous pacemakers), and other   nosis and therapy. Vet Clin North Am 40:665-684,
           •  Although IE and myxomatous/degenerative   conditions potentially causing endothelial   2010.
            valve endocardiosis can cause valve thicken-  damage should receive routine antibiotic   AUTHORS: Sandra P. Tou, DVM, DACVIM; Bruce W.
            ing and heart murmurs, the two conditions   prophylaxis for all procedures that are   Keene, DVM, MSc, DACVIM
            typically differ dramatically in patient signal-  likely  to  induce  transient  bacteremia.  By   EDITOR: Meg M. Sleeper VMD, DACVIM
            ment, history, murmur duration, location,   extrapolation from the current American
            quality, timing, and clinical presentation.  Heart  Association  Guidelines,  recom-
           •  A  high  index  of  suspicion  is  justified  for   mended antibiotic prophylaxis consists of
            any animal with fever (or history of fever)   a  single  oral  or  IV  antibiotic  dose  (e.g.,






            Entropion/Ectropion                                                      Client Education   Bonus Material
                                                                                                         Online
                                                                                           Sheet

            BASIC INFORMATION                     brachycephalic breeds, including Peking-  Clinical Presentation
                                                  ese, pug and shih tzu; brachycephalic cats
           Definition                           ○   Genetics not fully understood; most likely   DISEASE FORMS/SUBTYPES
           •  Entropion is inversion of part of or the entire   polygenic but could be inherited as a   •  Developmental:  secondary  to  abnor-
            eyelid margin toward the globe; it can be   dominant trait with incomplete penetrance   mal  or poor conformation, may be
            developmental or acquired.            or a recessive trait             congenital,  juvenile,  or  senile  (entropion
           •  Ectropion is eversion of part of or the entire   •  Developmental  ectropion:  bloodhound,   and ectropion)
            eyelid margin away from the globe; it can   Saint  Bernard,  Great  Dane,  bullmastiff,   •  Spastic (entropion)
            be developmental or acquired.       Newfoundland, and some spaniel breeds  •  Cicatricial (entropion and ectropion)
                                              •  Combination entropion-ectropion affecting
           Synonyms                             the same lid: bloodhound, Saint Bernard,   HISTORY, CHIEF COMPLAINT
           Inrolled  eyelid  (entropion);  everted  eyelid   and English bulldog  Entropion:
           (ectropion)                                                           •  Ocular discharge
                                              RISK FACTORS                       •  Blepharospasm
           Epidemiology                       •  Developmental  entropion  and  ectropion:   •  Red eye
           SPECIES, AGE, SEX                    breed predispositions            •  Visible inrolling of eyelid
           Entropion:                         •  Acquired entropion              •  ± Vision impairment in severe cases
           •  Common in dogs; rare in cats      ○   Conditions that stimulate blepharospasm   Ectropion:
           •  Can  occur  at  any  age;  developmental   (e.g., corneal ulceration)  •  Ocular discharge
            entropion usually occurs in dogs < 1 year    ○   Eyelid trauma       •  Red eye
            of age                              ○   Blepharitis                  •  Droopy/long lower eyelid
           •  Can  occur  at  any  age  in  cats  but  usually   ○   Older age and associated loss of orbital
            older cats                            fat (especially cats)          PHYSICAL EXAM FINDINGS
           Ectropion:                           ○   Phthisis bulbi (p. 705)      Entropion:
           •  Dogs  (variable  ages  depending  on  the     ○   Enophthalmos     •  Inversion  of  the  eyelid  and  any  of  the
            cause)                            •  Acquired ectropion                following:
                                                ○   Eyelid trauma                  ○   Conjunctivitis (pp. 199 and 200)
           GENETICS, BREED PREDISPOSITION       ○   Blepharitis                    ○   Epiphora, mucoid or mucopurulent ocular
           •  Developmental (conformational) entropion:  ○   Old age and associated loss of orbicularis   discharge
            ○   Lateral entropion: English bulldog, chow   oculi muscle tone       ○   Blepharospasm
              chow,  Shar-pei,  Saint  Bernard,  boxer,   ○   Facial nerve paralysis  ○   Protrusion of the third eyelid
              rottweiler,  pointers,  spaniels,  and  all                          ○   Nonulcerative keratitis (pp. 206 and 212)
              retrievers                      ASSOCIATED DISORDERS                 ○   Ulcerative keratitis (p. 209)
            ○   Medial canthal entropion: miniature and   •  Conjunctivitis        ○   Corneal sequestration in cats (p. 208)
              toy  poodles,  English  bulldog,  Cavalier   •  Keratitis (ulcerative and nonulcerative)  ○   Enophthalmos secondary to atrophy of
              King  Charles  spaniel,  Maltese,  and   •  See Risk Factors above     retrobulbar fat in cats

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