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Entropion/Ectropion   297


                                                                                  Initial Database
                                                                                  Complete ophthalmic exam (p. 1137):
  VetBooks.ir                                                                     •  Fluorescein dye application      Diseases and   Disorders
                                                                                  •  Schirmer tear test (normal > 15 mm after
                                                                                    1 minute in dogs, varies in cats)
                                                                                  •  Intraocular pressures
                                                                                  •  Careful examination of confirmation of eyelid
                                                                                    margins, conjunctiva, and cornea
                                                                                  Advanced or Confirmatory Testing
                                                                                  •  Varies,  depending  on  underlying  cause  of
                                                                                    entropion and/or ectropion
                                                                                  •  With  entropion,  apply  topical  anesthetic
                                                                                    (e.g.,  proparacaine  0.5%)  to  evaluate
                                                                                    degree of spastic entropion (i.e., entropion
                                                                                    secondary to ocular pain) vs. developmental
           ENTROPION/ECTROPION  Entropion of the ventral lateral eyelid of the right eye in a dog. Note the facial   entropion. Spastic entropion secondary to
           hairs (trichiasis) rubbing on the lateral corneal surface, causing corneal pigmentation and fibrosis (keratitis),   painful ocular disease such as ulcerative
           with mild ocular discharge adhered to the facial hairs.                  keratitis temporarily resolves or decreases in
                                                                                    severity within a few minutes of application.
                                                                                    Many dogs with developmental entropion
                                                                                    will also have a spastic component.
           Ectropion:                           ○   Scarring and contraction of the eyelid   •  Examine  animal  in  a  relaxed  state  to
           •  Eversion of the lower eyelid and some or all   from a previous eyelid injury and/or   determine extent of entropion and/or
             of the following:                    inflammation                      ectropion and to select most appropriate
             ○   Conjunctivitis                 ○   Facial nerve paralysis          corrective surgical procedure; restraining the
             ○   Keratitis                     Cats:                                animal or manipulation of the head during
             ○   Lagophthalmos (incomplete closure of the   •  Developmental entropion (rare)  examination can increase the severity of
               eyelids)                         ○   Medial  canthal  entropion  in  brachyce-  blepharospasm and exaggerate the degree of
                                                  phalic breeds                     entropion.
           Etiology and Pathophysiology        •  Acquired entropion
           Dogs:                                ○   Decreased orbital support associated with    TREATMENT
           •  Developmental entropion (conformational)  loss of orbital and periorbital fat predis-
             ○   Can be congenital or juvenile in onset  poses  to  loss  of  eyelid  support  (usually   Treatment Overview
             ○   Related to abnormal skull and palpebral   older cats) (involutional entropion)  •  Treatment  goals  for  entropion  include
               fissure (eyelid opening) conformation  ○   Secondary to blepharospasm, related to   resolution of underlying painful ocular
             ○   Associated with misdirection of the   conjunctival and corneal irritation (spastic)  disorders (e.g., conjunctivitis, keratitis) for
               lateral canthal ligament in mesaticephalic   ○   Associated with scarring and contraction   spastic entropion and surgical repair for
               (intermediate facial somatotype; neither   from chronic conjunctival and/or eyelid   developmental (conformational) entropion.
               brachycephalic nor dolichocephalic) breeds  inflammation (cicatricial)  •  Treatment goals for ectropion are to restore
             ○   Associated with ptosis and weight from                             normal lid conformation only if severe and
               excessive  dorsal  skinfolds:  upper  eyelid    DIAGNOSIS            predisposing to chronic ocular irritation and
               entropion                                                            keratitis. Mild ectropion is normal for many
             ○   Associated  with  microblepharon  (small   Diagnostic Overview     large-breed dogs.
               eyelids)                        The  diagnosis  of  entropion  is  based  on  the
           •  Acquired entropion               presence  of  ocular  irritation  (epiphora,  con-  Acute General Treatment
             ○   Decreased  orbital  support  (decreased   junctivitis, or keratitis) and is confirmed by   Entropion:
               orbital mass, phthisis bulbi, or retractor   identification  of  abnormal  lid  confirmation   •  Treat underlying condition(s).
               bulbi muscle contraction) predisposes to   (inversion  of  part  of  or  the  entire  eyelid).   •  Temporary  correction  in  puppies  until
               loss of lid support (involutional entropion)  Ectropion  is  diagnosed  on  physical  exam:   adult conformation reached (developmental
             ○   Secondary to blepharospasm and enop-  eversion of the lower eyelid. For both disorders,   entropion in puppies) or until underlying
               thalmus from pain (spastic entropion)  an ophthalmic exam is indicated to identify   condition resolved (spastic entropion)
             ○   Secondary to scarring and contraction   lesions caused by the eyelid malformation and   ○   Roll  eyelids  away  from  eye  by  placing
               of the eyelid from a previous eyelid   determine the cause of eyelid malformation.  temporary  tacking  (vertical  mattress
               injury  and/or  inflammation  (cicatricial                             sutures) or temporary tarsorrhaphy
               entropion)                      Differential Diagnosis                 sutures to prevent chronic ocular pain
           •  Developmental ectropion          Entropion:                             and blepharospasm and to prevent or
             ○   Mild ectropion is a desired feature in some   •  Usually diagnosed on clinical exam; must   treat corneal ulceration, pigmentation,
               breeds (i.e., hounds).           be differentiated from                vascularization, and scarring.
             ○   Related to abnormal skull and palpebral   ○   Distichiasis:  one  or  more  cilia  emerge   ○   If successful, condition may not require
               fissure confirmation               from the meibomian glands instead of   permanent repair.
             ○   Associated with laxity of the palpebral   the normal peripheral lid margin.  •  Permanent  surgical  correction  once  adult
               fissure related to macroblepharon  ○   Trichiasis:  normal  eyelid  or  facial  hair   confirmation is reached and no underlying
           •  Acquired ectropion                  directed  toward  and  contacting  the   condition (see Chronic Treatment)
             ○   Transient ectropion results from the laxity   conjunctiva or cornea
               of the eyelid from relaxation or following   Ectropion:            Chronic Treatment
               excessive exercise in breeds with long lower   •  Usually diagnosed based on clinical exam:   Chronic entropion in mature animals requires
               eyelids.                         apparent even before handling the patient  surgery to evert the eyelid margin. Procedures

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