Page 1214 - Small Animal Internal Medicine, 6th Edition

1186 PART IX Nervous System and Neuromuscular Disorders

VetBooks.ir Drugs Used in Neurologic Disorders—cont’d RECOMMENDED DOSE

DRUG NAME (TRADE
NAME) PURPOSE DOG CAT

Levetiracetam (Keppra) Anticonvulsant (chronic) 20 mg/kg PO q8h Same
Anticonvulsant (status 60 mg/kg IV Unknown
epilepticus)
Mannitol 20% Cerebral edema treatment 1-3 g/kg IV over 15 min Same
Meclizine Vestibulosedative antiemetic 1-2 mg/kg PO q24h Same
Methocarbamol (Robaxacin) Muscle relaxant 20 mg/kg PO q8-12h None
Methylprednisolone sodium Spinal trauma (acute) 20-40 mg/kg IV Same
succinate (SoluMedrol)
Metronidazole (Flagyl) Antibiotic 10-15 mg/kg PO q8h Same
7.5 mg/kg IV q8h Same
Mycophenolate mofetil Treat GME/Myasthenia 20 mg/kg PO q12h × 30 days, None
(CellCept) gravis then 10 mg/kg q12h
Neostigmine methylsulfate Myasthenia gravis treatment 0.04 mg/kg IM q6-8h Same
Testing for myasthenia gravis 0.01 mg/kg IV after premedicating Same
with atropine
Pentobarbital Anticonvulsant/anesthetic 5-15 mg/kg IV to effect Same
Phenobarbital Anticonvulsant 2.5-3 mg/kg PO q12h; adjust based Same
on blood level
Phenoxybenzamine Decrease urethral smooth 0.25-0.5 mg/kg PO q8h 2.5-5 mg/cat PO
muscle tone q12h
Potassium bromide Anticonvulsant 15-20 mg/kg PO q12h; adjust None
based on blood level
Potassium gluconate (Kaon Treat hypokalemia None 2.5-5 mEq PO q12h
Elixir)
Pralidoxime chloride (2-PAM) Treat organophosphate 20 mg/kg IM q12h Same
intoxication
Prednisone Immunosuppression 2-4 mg/kg PO q24h 2-6 mg/kg PO q24h
Antiinflammatory/antiedema 0.5-1 mg/kg PO q24h Same
Procainamide Myotonia 10-30 mg/kg PO q6h None
Propofol Anticonvulsant/anesthetic 4 mg/kg IV to effect Same
2
Procarbazine (Matulane) Treat GME 25-50 mg/m PO q24h × 30 days, None
then q48h
Pyrimethamine Toxoplasmosis 0.25-0.5 mg/kg PO q12h Same
Pyridostigmine bromide Myasthenia gravis 1-3 mg/kg PO q8h 0.25-1 mg/kg PO
(Mestinon) q12h
Trimethoprim/sulfadiazine Antibiotic 15 mg/kg PO q12h Same
(Tribrissen)
Xylazine (Rompun) Emetic (cats) None 0.44 mg/kg IM
Zonisamide (Zonegran) Anticonvulsant 5-10 mg/kg PO q12h

GME, Granulomatous meningoencephalomyelitis; IM, intramuscular; IV, intravenous; PO, by mouth; SC, subcutaneous.