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CHAPTER 14   Diagnostic Tests for the Nasal Cavity and Paranasal Sinuses   253





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               A                                               B

                          FIG 14.13
                          Rhinoscopic view through the external naris. (A) A single nasal mite is seen in this dog
                          with Pneumonyssoides caninum. (B) A thin white worm is seen in this dog with Capillaria
                          (Eucoleus) boehmi.


                                                                 cats, however, the diagnosis must be based on cytologic,
                   BOX 14.2                                      histologic, and microbiologic evaluation of nasal biopsy
            Differential Diagnoses for Gross Rhinoscopic         specimens. Nasal biopsy specimens should be obtained
            Abnormalities in Dogs and Cats                       immediately after nasal imaging and rhinoscopy while
                                                                 the animal is still anesthetized. These earlier procedures
             Inflammation (Mucosal Swelling, Hyperemia, Increased   can help localize the lesion, maximizing the likelihood of
               Mucus, Exudate)                                   obtaining  material  representative of  the  primary  disease
               Nonspecific finding; consider all differential diagnoses   process.
                  for mucopurulent nasal discharge (infectious,    Nasal biopsy techniques include nasal swab, nasal flush,
                  inflammatory, neoplastic)                      pinch biopsy, and turbinectomy. Fine-needle aspirates can
             Mass                                                be obtained from mass lesions as described in Chapter 74.
               Neoplasia                                         Pinch biopsy is the preferred nonsurgical method of speci-
               Nasopharyngeal polyp
               Cryptococcosis                                    men collection. It is more likely than nasal swabs or flushes
               Mat of fungal hyphae or fungal granuloma          to  provide  pieces  of  nasal  tissue  that  extend  beneath  the
                  (aspergillosis, penicilliosis, rhinosporidiosis)  superficial inflammation, which is common to many nasal
             Turbinate Erosion                                   disorders.  In  addition,  the  pieces  of  tissue  obtained with
               Mild                                              this more aggressive method can be evaluated histologi-
                  Feline herpesvirus                             cally, whereas the material obtained with the less traumatic
                  Chronic inflammatory process                   techniques may be suitable only for cytologic analysis.
               Marked                                            Histopathologic examination is preferred over cytologic
                  Aspergillosis                                  examination in most cases because the marked inflamma-
                  Neoplasia                                      tion that accompanies many nasal diseases makes it diffi-
                  Cryptococcosis                                 cult to cytologically differentiate primary from secondary
                  Penicilliosis
             Fungal Plaques                                      inflammation and  reactive  from neoplastic epithelial  cells.
               Aspergillosis                                     Carcinomas can also appear cytologically as lymphoma and
               Penicilliosis                                     vice versa.
             Parasites                                             Regardless of the technique used (except for nasal swab),
               Mites: Pneumonyssoides caninum                    the cuff of the endotracheal tube should be inflated (avoid-
               Worms: Capillaria (Eucoleus) boehmi               ing overinflation) and the caudal pharynx packed with
             Foreign Bodies                                      gauze sponges to prevent the aspiration of fluid. Intravenous
                                                                 crystalloid fluids (10-20 mL/kg/h plus replacement of esti-
                                                                 mated blood loss) are recommended during the procedure
                                                                 to counter the hypotensive effects of prolonged anesthesia
            NASAL BIOPSY: INDICATIONS                            and blood loss from hemorrhage after biopsy. Blood-clotting
            AND TECHNIQUES                                       capabilities should be assessed before the more aggressive
                                                                 biopsy techniques are performed if there is any history of
            Visualization of a foreign body or nasal parasites during   hemorrhagic exudate or epistaxis or any other indication of
            rhinoscopy  establishes  a  diagnosis.  For  many  dogs  and   coagulopathy.
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