Page 401 - Small Animal Internal Medicine, 6th Edition
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CHAPTER 24   Disorders of the Pleural Cavity and Mediastinum   373


            adequate drainage and should be assessed by radiography   are seen on thoracic radiographs, the chest tube is removed
            or ultrasonography. No obvious benefit is derived from the   and the animal is monitored clinically for at least 24 hours
  VetBooks.ir  addition of antibiotics, antiseptics, or enzymes to the lavage   for the development of pneumothorax or the recurrence of
                                                                 effusion. Thoracic radiographs can be taken to more sensi-
            solution. The addition of heparin (1000-1500 U/100 mL) to
            the lavage fluid may decrease fibrin formation and has been
                                                                   Thoracic radiographs are evaluated 1 week after removal
            associated with better outcomes (Boothe et al., 2010).  tively evaluate the animal for these potential problems.
              All adapter ports connected to the chest tube should be   of the chest tube and 1 week and 1 month after discontinu-
            covered with sterile caps when not in use. When accessing   ation of antibiotic therapy. These radiographs are obtained
            the ports, the clinician should wear gloves and remember to   so that a localized nidus of disease such as a foreign body or
            wipe the ports with hydrogen peroxide before use.    an abscess can be identified, and so that recurrence of a
              Thoracic radiographs are taken every 24 to 48 hours to   pyothorax can be detected before large volumes of pleural
            ensure that the chest is being completely drained of fluid.   fluid accumulate. Such niduses are often invisible when large
            Failure to monitor the effectiveness of drainage radiographi-  volumes of pleural fluid are present or when aggressive
            cally can lead to costly prolongation of the intensive care   therapy is in progress.
            required for maintenance of the chest tube.            Exploratory thoracotomy is indicated for the removal of
              Serum electrolyte concentrations are also monitored.   a suspected nidus of infection and in those animals that do
            Many dogs and cats with pyothorax are dehydrated and ano-  not respond to medical therapy. In the latter instance, surgery
            rectic at presentation and require intravenous fluid therapy.   may be necessary to remove fibrotic and diseased tissue or a
            Supplementation of the intravenous fluid with potassium   foreign body. Failure to respond is suggested by the contin-
            may be necessary.                                    ued need for a chest tube for longer than 1 week after the
              The decision to discontinue drainage and remove the   start of appropriate antibiotic treatment and drainage,
            chest tube is based on fluid volume and cytologic character-  although reported cases that have undergone complete
            istics. The volume of fluid recovered should have decreased   recovery after medical management have required drainage
            to less than 2 mL/kg/day. Slides of the fluid are prepared   by chest tubes for longer periods. Furthermore, persistence
            daily and evaluated cytologically. Bacteria should no longer   of large pockets of fluid in spite of appropriate chest tube
            be visible intracellularly or extracellularly. Neutrophils will   placement may necessitate the decision to perform a thora-
            persist but should no longer appear degenerative (Fig. 24.3).   cotomy earlier. Computed tomography of the chest may be
            When these criteria have been met and no pockets of fluid   a more sensitive method than thoracic radiography for



































                          FIG 24.3
                          Cytologic preparation of a specimen of a pleural effusion from a cat being treated
                          successfully for pyothorax with chest tube drainage and antibiotics. Compared with the
                          fluid shown in Fig. 24.1, the nucleated cell count is low, the neutrophils are
                          nondegenerative, organisms are not present, and mononuclear cells are appearing
                          (cytocentrifuge prep).
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