Page 1301 - Veterinary Immunology, 10th Edition

VetBooks.ir Immunodeficiencies of Horses

Horses are among the few domestic animals whose economic worth
has permitted a thorough analysis of neonatal mortality. As a

result, a significant number of primary immunodeficiency
syndromes have been identified in this species (Fig. 39.6).

FIG. 39.6 The differential diagnosis of the equine immune
deficiencies.

Severe Combined Immunodeficiency

The most important congenital equine immunodeficiency is severe
combined immunodeficiency (SCID). Affected foals fail to produce
functional T or B cells and have very few circulating lymphocytes.

If they suckle successfully, they acquire maternal immunoglobulins.
Once these have declined, however, these foals cannot produce

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