Page 1485 - Veterinary Immunology, 10th Edition

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CD4 T cells.
VetBooks.ir conventional TCR α/β locus in that its V genes are more related to
Chickens also possess a second TCRδ locus that differs from the

IgH V genes than to TCR V genes. In this it resembles the

marsupial/monotreme TCRµ locus.
Birds reject skin allografts in about 7 to 14 days. Histological
examination shows massive infiltration of the grafted tissue with
lymphocytes. These cells are believed to be T cells since neonatal

thymectomy results in a failure to reject grafts. If chicken T cells are
dropped onto the chorioallantoic membrane of 13- to 14-day-old
chick embryos, the cells will attack the chick tissues. This will result
in pock formation on the membrane and splenic enlargement. The

grafted cells attack the hematopoietic cells of the recipient. A few
days after hatching, chicks become resistant to this form of graft-
versus-host attack.

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