Page 1529 - Veterinary Immunology, 10th Edition

for antigen that occurs during the course of an immune response
VetBooks.ir as a result of somatic mutation in V genes.

Agammaglobulinemia The absence of γ-globulins in blood.

Agglutination The clumping of particulate antigens by antibodies.

Agnatha A class of jawless fish. It includes the cyclostomes, an
order containing the hagfish and lamprey.

Alarmins Molecules released by dead or damaged tissues that
trigger innate immune responses, especially inflammation. See

also Damage-associated molecular patterns (DAMPs).

Albumin The blood protein largely responsible for maintaining

plasma osmotic pressure.

Alleles Different forms of a gene that occupy the same

polymorphic locus.

Allelic exclusion The expression of only one allelic protein by a cell

from a heterozygous individual that has the genes to express
both allelic proteins.

Allergens Antigens that provoke allergic reactions. Usually type I
hypersensitivity.

Allergic contact dermatitis An inflammatory skin reaction
mediated by Th1 cells responding to low-molecular-weight
chemicals bound to skin cells.

Allergy A hypersensitivity reaction initiated by specific
immunological mechanisms.

Allogeneic Genetically dissimilar animals of the same species.

Allograft An organ graft between two genetically dissimilar
animals of the same species.

Allotype Phenotypic (antigenic and structural) differences between
the proteins of different individuals of the same species as a
result of transcription of different alleles.

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