Page 1534 - Veterinary Immunology, 10th Edition

VetBooks.ir Cell-mediated cytotoxicity The killing of target cells induced by

contact with cytotoxic T cells, NK cells, or macrophages.

Cell-mediated immunity A form of immune response mediated by

T lymphocytes and macrophages; it can be conferred on an
animal by adoptive transfer.

Cestodes Parasitic tapeworms.

Checkpoint therapy A cancer treatment that uses monoclonal

antibodies to enhance T cell cytotoxicity and to destroy cancer
cells.

Chemokine A family of proinflammatory and chemotactic
cytokines with a characteristic sequence of four cysteine
residues. They regulate the emigration of leukocytes from blood
into tissues.

Chemotaxis The directed movement of cells under the influence of
a chemical concentration gradient.

Chimera An animal that contains cells from two or more
genetically different individuals.

Chondrichthyes The class that contains the cartilaginous fishes,

including sharks, skates, and rays.

Chromosome translocation A form of mutation in which portions

of two chromosomes switch positions.

Chronic inflammation Slowly developing or persistent

inflammation characterized by tissue infiltration with
macrophages and fibroblasts.

Class The five major forms of immunoglobulin molecules common

to all members of a species (see Isotype). Each has its own set of
heavy chain genes.

Class switch The change in immunoglobulin class that occurs
during the course of an immune response as a result of heavy
chain gene rearrangement.

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