Page 1535 - Veterinary Immunology, 10th Edition

VetBooks.ir Classical complement pathway The complement pathway

triggered by activation of C1 by antigen-antibody complexes.

Clonal deletion The elimination of self-reactive T cells in the

thymus.

Clonal selection A key concept in immunology. The proliferation

of specific lymphocyte clones in response to a specific epitope.
The response is triggered through specific antigen-binding
receptors.

Clone The progeny of a single cell.

Clonotype A clone of B cells with the ability to bind a single
epitope.

Cluster of differentiation (CD) The set of monoclonal antibodies
that recognize a single protein on a cell surface. A CD antigen is
by extension, therefore, a defined protein on the surface of a cell.

Coelomocyte A phagocytic cell found in the coelomic cavity of
invertebrates.

Collectins A family of carbohydrate-binding lectins that depend on
calcium for their adhesion.

Colostrum The secretion that accumulates in the mammary gland
in the last weeks of pregnancy. It is very rich in

immunoglobulins.

Combined immunodeficiency A deficiency in both the T cell– and

B cell–mediated components of the immune system.

Commensal Two species that live together and share resources.

Complement A group of serum and cell surface proteins activated
by factors such as the combination of antigen and antibody and

results in the generation of enzyme cascades that have a variety
of biological consequences, including cell lysis and opsonization.

Complementarity determining region Those areas within the

variable regions of antibodies and T cell antigen receptors that

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