Page 426 - Problem-Based Feline Medicine
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418  PART 7   SICK CAT WITH SPECIFIC SIGNS


          Lymph nodes are normal during chronic experimental
                                                        CYTAUXZOONOSIS
          infection.
          Bacteria resembling B. henselae have been seen in  Classical signs
          some clinical cases with moderate to marked lymph-
                                                         ● Fulminant disease with fever and
          adenopathy due to atypical hyperplasia.
                                                           hemolytic anemia.
          Diagnosis                                     See main reference page 389 (The Pyrexic Cat).

          Lymph node biopsy reveals follicular hyperplasia in
                                                        Clinical signs
          grossly normal lymph nodes during chronic experimen-
          tal infection.                                Acute onset of fever, lethargy, inappetence, dyspnea,
                                                        anemia and jaundice.
          Silver staining of lymph nodes of cats with lymph-
          adenopathy may reveal bacteria. In such cases blood  Lymphadenopathy is usually identified at necropsy.
          culture and/or serologic testing and/or PCR testing for
          B. henselae should be performed.              Diagnosis
                                                        Exposure history (tick exposure in south-central or
                                                        south-eastern North America).
          PROTOTHECOSIS
                                                        Identification of the protozoan, Cytauxzoon felis, on
                                                        red cells, as tiny dot, tetrad, safety-pin or signet ring
           Classical signs
                                                        forms.
           ● Firm cutaneous nodule on foot.
                                                        Lymph node histology reveals hemorrhage and edema.

          Clinical signs                                ANTHRAX
          Large firm cutaneous nodule(s), which may be ulcer-
          ated, on foot, limb, head or base of tail. Nodules are not  Classical signs
          painful on palpation, but may cause discomfort and
                                                         ● Edema of the head and neck.
          other signs from local mass effect.
                                                         ● Acute death with no promontory signs.
          Local lymph node is usually normal.
          No systemic signs.                            Clinical signs

                                                        Rare – cats are resistant to anthrax.
          Diagnosis                                     Lingual and pharyngeal edema cause oral serosan-
                                                        guineous discharge and dyspnea.
          Cytology and histology of biopsy specimens reveal
          granulomatous inflammation.                   Cervical regional lymphadenopathy due to edema,
                                                        hemorrhage and necrosis may occur.
          Lymph node biopsy may reveal hyperplasia or lymph-
          adenitis.                                     In one case acute death occurred with no promontory
                                                        signs and there were no significant necropsy findings
          Identification of Prototheca sp. (algae), in specimens by
                                                        other than congested lungs and unclotted blood.
          cytology, histology or culture.
          ● Mature organisms are round, have a hyaline cell
                                                        Diagnosis
            wall, small central nucleus, may show internal cleav-
            age into endospores, and vary from smaller to larger  History of  ingesting potentially contaminated raw
            than neutrophils.                           meat or animal by-products.
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