Page 430 - Problem-Based Feline Medicine

422 PART 7 SICK CAT WITH SPECIFIC SIGNS

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IMMUNE

● Immune-mediated anemia (p 424)
Jaundice, lethargy, inappetance, occasional vomiting, and respiratory distress with severe ane-
mia.
HEPATIC
● Jaundice caused by primary hepatic parenchymal diseases.
DEGENERATIVE

● Cirrhosis (p 435)
Rare and usually follows severe chronic hepatopathy. Jaundice, anorexia, weight loss and/or
hepatomegaly.
METABOLIC
● Diabetes mellitus (p 436)
Polyuria, polydipsia, increased appetite, weight loss, plantigrade stance with neuropathy.
● Hyperthyroidism (p 437)
Generally seen in cats greater than 8 years old. Often have an increased appetite, weight loss, poor
hair coat, vomiting.
● Hepatic lipidosis*** (p 425)
Often previous history of obesity and/or anorexia. Jaundice, weight loss, and anorexia are
common.
NEOPLASTIC

● Lymphosarcoma* (p 431)
Usually a manifestation of multicentric lymphosarcoma. Jaundice, anorexia, weight loss, vomiting
and/or diarrhea.
● Non-hematopoietic liver tumors (biliary cyst adenoma, hepatocellular carcinoma) (p 436)
Vast majority are benign tumors seen in old cats. Anorexia, lethargy, and weight loss
predominate.
INFLAMMATION
● Feline cholangitis (cholangitis/cholangiohepatitis syndrome)*** (p 427)
The neutrophilic form is seen most commonly in male cats. It may be associated with other
inflammatory disorders (IBD, pancreatitis) concurrently affecting the gastrointestinal tract. It
occurs as an acute phase associated with signs of systemic illness such as fever, anorexia,
lethargy, vomiting and jaundice. Signs in the chronic phase are milder and weight loss domi-
nates. The lymphocytic form is associated with jaundice, hepatomegaly, vomiting, diarrhea
and/or ascites.