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                                                                 Dorsal funiculus
  VetBooks.ir  Marginal zone  Intermediate zone    Lateral funiculus       Dorsal horn













           Neural canal
                        Ventricular zone              Ventral funiculus     Ventral horn
                                                                  Central canal
          Figure 10-6.  Cross‐sectional view of the development of the spinal cord.


                    3 vesicle stage       5 vesicle stage        Adult structures


                                                    Telencephalon  Cerebral hemispheres

                                                    Diencephalon   Thalamus and hypothalamus
           Prosencephalon
                                                    Mesencephalon  Midbrain
            Mesencephalon
                                                    Metencephalon  Pons and cerebellum
          Rhombencephalon

                                                    Myelencephalon  Medulla oblongata
               Spinal cord

                                                    Spinal cord



          Figure 10-7.  Dorsal view of the neural tube. The early brain divides into three vesicles that further
            differentiate into five vesicles. These give rise to the main regions of the adult brain. Notice the optic cups
          (primitive retinae and optic nerves) developing from the diencephalon.

          cord. The white color comes from the fatty   These subdivisions, which consist of three
          myelin sheaths. The spinal cord white mat-  dilations of the presumptive brain, are the
          ter is divided into dorsal, lateral, and ven-  prosencephalon, or forebrain; mesenceph-
          tral funiculi, which are delimited by the   alon, or midbrain; and rhombencephalon,
          dorsal and ventral horns of gray matter.  or hindbrain. The prosencephalon devel-
            Development of the brain (Fig.  10‐7)   ops lateral extensions, the  optic vesicles,
          begins before the neural tube is fully closed   the precursors of the optic nerves and
          caudally. It grows rapidly throughout   retinas.
          embryonic and fetal life and into the neona-  With further development, the three ves-
          tal  period.  The  first  gross  subdivisions  of   icles differentiate into five distinct regions.
          the brain create the three vesicle stage.   In this five‐vesicle stage of development, the
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