Page 316 - Clinical Small Animal Internal Medicine
P. 316

284  Section 3  Cardiovascular Disease

              when indicated. The fluid in the red‐top tube should be   results. Balloon pericardiotomy has been described as a
  VetBooks.ir  monitored for clotting, which could indicate inappropri-  palliative procedure for neoplastic effusions.
              ate intracardiac placement of the catheter. Pericardial
              fluid does not routinely clot. A packed cell volume
              (PCV) on the effusion can be obtained to confirm that   Prognosis
              the fluid is not blood.                         Prognosis depends on the underlying cause of the effu-
            7)  Once pericardial effusion is no longer withdrawn,   sion. Pericardiectomy can result in clinical improvement
              ultrasound can be used to confirm the pericardial   or cure in idiopathic cases and in infectious cases when
              effusion has been removed or has drained into the   combined with appropriate antibiotic or antifungal ther-
              thoracic cavity. Pleural effusion can be removed prior   apy. Pericardiectomy extends survival time in dogs with
              to withdrawing the catheter from the thorax.    heart base tumors and is associated with minimal
                                                              improvement with hemangiosarcoma and mesotheli-
            Monitoring and Follow‐Up                          oma. In cats, prognosis with effusion secondary to heart
            Pericardiocentesis often results in immediate clinical   disease and heart failure is guarded to poor due to the
            improvement. Careful monitoring of the patient for fur-  presence of severe underlying heart disease.
            ther hemodynamic collapse or clinical improvement is
            recommended following the procedure. Ideally, dogs
            should not be sent home immediately after pericardiocen-    Constrictive Pericarditis
            tesis and are monitored in the hospital for 12–24 hours.
            Rapid (minutes  to hours) reaccumulation of pericardial   Etiology/Pathophysiology
            fluid and significant arrhythmias are possible following
            pericardiocentesis. If pericardiectomy is not scheduled   Constrictive pericarditis is characterized by a stiff,
            (see Surgical Management for recommendations), recheck   fibrous pericardium that impairs ventricular diastolic
            within 2–4 weeks and consider pericardiectomy if the   filling even if no fluid is present. Although considered
            pericardial effusion has reaccumulated.           uncommon, the diagnosis is difficult to make and can
                                                              be overlooked. It is characterized by an absence of peri-
                                                              cardial effusion though combined constrictive‐effusive
            Cancer Therapy                                    disease does occur. Chronic pericardial and pleural

            Palliative or definitive cancer therapy rarely is successful   effusion including chylous effusion and infectious peri-
            with cardiac neoplasia. Complete surgical excision can   carditis secondary to fungal organisms can result in
            rarely be achieved because of tumor proximity to vital   constrictive pericarditis.
            structures. There are reports of a positive response to
            chemotherapy for lymphoma and hemangiosarcoma.    Signalment
            Consultation with an oncologist is recommended for the   Similar to pericardial effusion.
            most current therapeutic strategies.
                                                              History and Clinical Signs
            Surgical Management
                                                              Similar to pericardial effusion with a high incidence of
            Despite fluid removal and immediate clinical improve-  signs of elevated right heart pressures.
            ment, pericardial effusion is likely to recur in most
            instances. Surgical pericardiectomy (partial or subtotal)   Diagnosis
            allows improved visualization for the surgeon to iden-
            tify  the underlying etiology and/or biopsy a tumor.   Echocardiography
            Echocardiography is very specific for identifying a tumor   Pericardial effusion is often absent or small volume.
            but not 100% sensitive, particularly for small tumors that   Tamponade may be documented with only a small vol-
            may be readily identified by a surgeon. A small pericar-  ume of effusion. The pericardium can appear thickened.
            dial window provides palliation but can potentially lead   Advanced Doppler studies show respiratory changes in
            to constrictive pericarditis of the remaining pericardium   the peak velocities of mitral and tricuspid valve inflow
            or allow herniation of a portion of the heart through the   profiles highly suggestive of constrictive physiology.
            pericardial opening. Pericardiectomy can be curative for
            idiopathic and infectious etiologies and extend survival   Cardiac Catheterization
            for dogs with chemodectomas. Thoracoscopic pericar-  Characteristic patterns in atrial and ventricular pressure
            diectomy has the benefit of offering lower patient mor-  profiles are indicative of constrictive physiology although
            bidity but requires a skilled operator to achieve optimum   administering a fluid bolus may be required to generate
   311   312   313   314   315   316   317   318   319   320   321