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Hepatobiliary Disease 1179
VetBooks.ir Table 68-12. Levels of key nutritional factors in selected commercial veterinary therapeutic foods marketed for feline patients with
hepatobiliary disease, compared to recommended levels.*
Energy
Dry foods
Zinc
Vit. E
Vit. C
Iron
density Energy Protein Arginine Taurine Sodium (mg/kg) (mg/kg) (IU/kg) (mg/kg)
density
(%)
(%)
(%)***
(%)
(kcal/cup)** (kcal ME/g)
Recommended levels – ≥4.2 30-35 1.5-2.0 ≥0.3 0.07-0.30 >200 80-140 ≥500 100-200
Hill’s Prescription Diet
l/d Feline 505 4.5 31.8 1.98 0.53 0.27 305 173 267 109
Medi-Cal Mature Formula 355 na 29.2 na 0.4 0.4 na na na na
Medi-Cal Reduced Protein 440 na 28.1 na 0.4 0.3 na na na na
Medi-Cal Renal LP 21 409 na 24.7 na 0.2 0.2 na na na na
Purina Veterinary Diets EN
GastroENteric 572 4.4 56.2 na 0.32 0.64 na na 232 na
Royal Canin Veterinary Diet
Modified Formula 432 4.7 27.1 1.51 0.23 0.23 320 241 380 na
Moist foods Energy Energy Protein Arginine Taurine Sodium Zinc Iron Vit. E Vit. C
density density (%)*** (%) (%) (%) (mg/kg) (mg/kg) (IU/kg) (mg/kg)
(kcal/can)** (kcal ME/g)
Recommended levels – ≥4.2 30-35 1.5-2.0 ≥0.3 0.07-0.30 >200 80-140 ≥500 100-200
Hill’s Prescription Diet
l/d Feline 183/5.5 oz. 4.7 31.6 2.00 0.52 0.20 336 212 836 124
Medi-Cal Mature Formula 205/170 g na 41.5 na 0.3 0.3 na na na na
Medi-Cal Reduced
Protein 265/170 g na 33.9 na 0.3 0.2 na na na na
Medi-Cal Renal LP 125/85 g pouch na 29.3 na 0.8 0.6 na na na na
Royal Canin Veterinary 256/170 g
Diet Modified Formula 596/396 g 6.1 34.7 2.07 0.28 0.28 208 545 178 na
Key: ME = metabolizable energy, Vit. E = vitamin E, Vit. C = vitamin C, na = information not available from manufacturer.
*From manufacturers’ published information or calculated from manufacturers’ published as fed values; all values are on a dry matter basis
unless otherwise stated.
**Energy density values are listed on an as fed basis and are useful for determining the amount to feed; cup = 8-oz. measuring cup. To
convert to kJ, multiply kcal by 4.184.
***For liver disease patients with signs of hepatic encephalopathy (HE), dietary protein levels should be limited to 25 to 30% dry matter
until signs resolve. In these cases, several commercial veterinary therapeutic foods designed for patients with kidney disease that provide
less protein than the foods intended for liver disease may be appropriate (Chapter 37). If these foods are used, the patient should be transi-
tioned to the selected food specifically formulated for liver disease after signs of HE have subsided.
agents that are sometimes considered for liver disease patients. nasogastric or gastrostomy tube remains the cornerstone of
Anorectic cats with cholangitis or hepatic lipidosis will need therapy for feline patients with hepatic lipidosis and all other
to be fed via assisted-feeding techniques until they resume eat- anorectic patients with liver disease. Chapter 25 details foods
ing on their own. This dictates the use of nutrient-dense foods and enteral feeding techniques commonly used in dogs and
with textures intended for assisted feeding (Chapter 25).These cats. Patients that are eating enough food to meet their daily
patients should be fed a food intended for dietary management energy requirement (DER) can usually be managed at home.
of other hepatic diseases after they start eating (Table 68-12). The DER for cats with hepatic lipidosis should be at least
Another criterion for selecting a food that may become the resting energy requirement (RER) for ideal body weight
increasingly important in the future is evidence-based clinical when cats are managed in the hospital and 1.1 to 1.2 x RER
nutrition. Practitioners should know how to determine risks when managed at home. The DER of canine liver disease
and benefits of nutritional regimens and counsel pet owners patients managed at home should be approximately 1.2 to 1.4
accordingly. Currently, veterinary medical education and con- x RER. Young patients with congenital shunts may be stunted
tinuing education are not always based on rigorous assessment or underweight. DER calculations for these patients should be
of evidence for or against particular management options. Still, based on ideal rather than current body weight. These calorie
studies have been published to establish the nutritional benefits values can be converted to an amount of food to eat by divid-
of certain pet foods. Chapter 2 describes evidence-based clini- ing the energy density of the food (as fed basis) by the DER.
cal nutrition in detail and applies its concepts to various veteri- The as fed energy density (in cups or cans) of foods for liver
nary therapeutic foods. disease can be found in Tables 68-11 and 68-12.
Multiple daily feedings rather than one or two large meals
Assess and Determine the Feeding Method may benefit patients with hepatobiliary disease. Multiple daily
Sick, anorectic and severely malnourished patients with hepa- meals minimize the release of free fatty acids from adipose tis-
tobiliary disease should be hospitalized to initiate supportive sue, improve digestibility and reduce the quantity of ingesta at
care and assisted-feeding techniques. Early tube feeding via any one time that enters the colon where bacterial fermentation