Page 1204 - Small Animal Clinical Nutrition 5th Edition
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1254       Small Animal Clinical Nutrition


                  3. Excessive supplementation with vitamin D allows large amounts of calcium to be absorbed from the intestinal tract.The result-
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                    ing soft tissue mineralization, however, can be widespread and severe. Endstage renal failure is generally unresponsive to treat-
        VetBooks.ir  Progress Notes
                    ment; however, diuresis may provide short-term palliative treatment.

                  The iguana was diuresed with a mixture of 0.9% saline, 2.5% dextrose and lactated Ringer’s solution administered intracoelomical-
                  ly for two days. Unfortunately, the patient died on Day 3. Results of a necropsy examination revealed moderate tubular nephrosis
                  and severe degeneration with mineralization and necrosis of the heart and skeletal muscles.The final diagnosis was vitamin D tox-
                  icosis. Vitamin D and calcium metabolism are still not well elucidated in iguanas and vitamin D requirements have not been
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                  established. It is unclear how well vitamin D is absorbed in these animals. The risk of over-supplementation can be avoided by
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                  providing exposure to adequate amounts of ultraviolet-B light, thus allowing the body to form its own vitamin D instead of giv-
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                  ing oral supplementation.
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