Page 1064 - The Toxicology of Fishes

1044 The Toxicology of Fishes

mineralocorticoid receptors, 257, 463 gonopodium in, 470
mineralocorticoids, 474 insecticide-resistant, 625
mining, 35, 603, 779–801 mercury, and, 623
minnows (Phoxinus phoxinus), tributyltin oxide, Gambusia affinis, 69, 80, 213, 444, 608
and, 442 ciguatera toxins, and, 444
mirex, 91, 129, 810, 824 disease resistance in, 608–609
mirror carp (Cyprinus carpio), see carp: Cyprinus Gambusia holbrooki, nonylphenol, and, 990
carpio motorneurons, 419, 430, 434, 439, 445
miticides, 744 Mozambique tilapia, 403
mitochondria, 155, 277, 279, 287, 292, 336, 374, mRNA
407, 409, 441 CYP1A, 688
electron transport in, 299, 301 expression, reactive oxygen species and, 288
mitogen-activated protein kinases, 463, 557, 558 Mrp2, 89, 362, 365
mixed-function oxidase, 175, 375, 376, 609, 688, MTF-1, 258
947 mucosa, 79, 492–493
mixed-function oxygenases, 410, 944, 945, 947, goblet cells, 69
954–955 intestinal, 119, 174
MOAT, 191 mucosal tissues, 490
model error, 768, 770 mucosal weight, 69
model parameterization, 118–122 mucous glands, 75, 112
modeling, exposure, 645–657 mucous membranes, irritation of, 428, 437
molecular size, renal tubule secretion and, 88 mucus, 14, 69, 75–76, 90
molecular weight, 39, 42, 60, 72, 85, 86, 88, 184, hypersecretion of, 707
202, 203, 279, 281, 283–286, 352, 458, 678, Mugil cephalus, see mullet
881, 897 mullet (Mugil cephalus), 192, 193, 196, 374, 376
Mollusca, 198 acetaminophen, and, 370
mollusks, 131, 191, 444 carbon tetrachloride, and, 371
molybdozyme, 179 ceruloplasmin in, 286
monoamine neurotransmitters, 458 glutathione depletion in, 304
monoamine oxidases, 178 Mullus barbatus, 363
monochlorobenzene, 371 multidrug resistance (MDR), 691–692; see also P-
monoclonal antibody (mAb), 162, 489, 490, 512 glycoprotein (Pgp)
monocytes, 490, 491, 494, 495, 510 multidrug resistance-associated proteins (Mrps),
monodeiodinases, 476, 477 63, 84–85, 191, 361, 363
monoiodotyrosine (MIT), 477 Multispecies Freshwater Biomonitor, 708
monooxygenases, 211, 373, 511, 574, 605, 688 multivariate methods, 746, 747
monooxygenation, 213, 301 multixenobiotic resistance (MXR), 691
Monte Carlo analysis, 123, 656, 770–771 mummichog (Fundulus heteroclitus), 44, 204,
moray eel (Gymnothorax funebris), dermal 205, 329, 362, 954; see also killifish
sarcoma in, 548 allozymes in, 623
Morone americana, 558 Atlantic Wood, 618–620, 621, 622, 627
Morone chrysops, 129; see also white bass creosote contamination, and, 372
Morone saxatilis, 178, 444, 499; see also striped creosote-resistant, 623
bass CYP1A, and, 351, 366
morphants, 250, 832, 834 dioxin-like compounds, and, 611–616, 623
morphogenesis, 418, 420 endocrine disruption in, due to pulp mill
morpholino-modified oligonucleotides, 249, 250, effluent, 954
256 glutathione S-transferase in, 712
morpholino oligonucleotide, 828, 832, 833 hepatic neoplasms in, 577
morphological abnormalities, 709–711 hepatocellular carcinoma in, 618
mosquitofish, 91, 735 immune assays, 498
cadmium, and, 623 kepone, and, 609
copper, and, 623 mercury, and, 611