Page 1252 - Saunders Comprehensive Review For NCLEX-RN

Client Needs: Physiological Integrity
Integrated Process: Nursing Process—Assessment
Content Area: Pharmacology: Integumentary: Burn Products
Health Problem: Adult Health: Integumentary: Burns
Priority Concepts: Gas Exchange; Tissue Integrity
Reference: Ignatavicius, Workman, Rebar (2018), p. 501.

437. Answer: 2

Rationale: Isotretinoin can elevate triglyceride levels. Blood triglyceride levels
should be measured before treatment and periodically thereafter until the effect on
the triglycerides has been evaluated. There is no indication that isotretinoin affects
potassium, hemoglobin A C, or total cholesterol levels.
1
Test-Taking Strategy: Note the subject, laboratory values that should be
monitored specifically for the client taking isotretinoin. Recall that the medication
can affect triglyceride levels in the client.
Level of Cognitive Ability: Analyzing
Client Needs: Physiological Integrity
Integrated Process: Nursing Process—Assessment
Content Area: Pharmacology: Integumentary: Acne Products
Health Problem: Adult Health: Integumentary: Inflammations/Infections
Priority Concepts: Cellular Regulation; Tissue Integrity
Reference: Lewis et al. (2017), pp. 417, 419.

438. Answer: 3

Rationale: Isotretinoin is a metabolite of vitamin A and can produce generalized
intensification of isotretinoin toxicity. Because of the potential for increased toxicity,
vitamin A supplements should be discontinued before isotretinoin therapy. There
are no contraindications associated with digoxin, phenytoin, or furosemide.
Test-Taking Strategy: Focus on the subject, the need to contact the PHCP to
ensure client safety. Recall that isotretinoin is a metabolite of vitamin A. Vitamin A is
a fat-soluble vitamin, and therefore it is possible to develop toxic levels. This will
direct you to the correct option.
Level of Cognitive Ability: Analyzing
Client Needs: Safe and Effective Care Environment
Integrated Process: Nursing Process—Implementation
Content Area: Pharmacology: Integumentary: Acne Products
Health Problem: Adult Health: Integumentary: Inflammations/Infections
Priority Concepts: Collaboration; Safety
Reference: Burchum, Rosenthal (2016), p. 1283.

439. Answer: 1, 4, 5

Rationale: Topical corticosteroids can be absorbed into the systemic circulation.
Absorption is higher from regions where the skin is especially permeable (scalp,
axilla, face, eyelids, neck, perineum, genitalia), and lower from regions where

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