Page 1441 - Saunders Comprehensive Review For NCLEX-RN

CHAPTER 47

Endocrine Medications

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Priority Concepts
Glucose Regulation; Hormonal Regulation

I. Pituitary Medications
A. Description
1. The anterior pituitary gland secretes growth hormone
(GH), thyroid-stimulating hormone (TSH),
adrenocorticotropic hormone (ACTH), prolactin,
melanocyte-stimulating hormone (MSH), and
gonadotropins (follicle-stimulating hormone [FSH]
and luteinizing hormone [LH]).
2. The posterior pituitary gland secretes antidiuretic
hormone (vasopressin) and oxytocin.
B. Growth hormones and related medications (Box 47-1)
1. Uses
a. Growth hormones are used to treat
pediatric or adult growth hormone
deficiency.
b. Growth hormone receptor antagonists
are used to treat acromegaly.
c. Growth hormone–releasing factor is
used to evaluate anterior pituitary
function.
2. Side and adverse effects
a. May vary depending on the medication
b. Development of antibodies to growth
hormone
c. Headache, muscle pain, weakness,
vertigo
d. Diarrhea, nausea, abdominal
discomfort
e. Mild hyperglycemia
f. Hypertension
g. Weight gain
h. Allergic reaction (rash, swelling), pain
at injection site
i. Elevated aspartate aminotransferase

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