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P. 1599

FIG. 50-3  Pathophysiology in asthma. Stems with asterisks are primary processes. IgE,
                                                     Immunoglobulin E.





               Box 50-4

               Asthma Triggers

               Environmental Factors


                  ▪ Animal dander
                  ▪ Cockroaches
                  ▪ Dust
                  ▪ Exhaust fumes

                  ▪ Fireplaces
                  ▪ Molds
                  ▪ Perfumes or other products with aerosol sprays
                  ▪ Pollen
                  ▪ Smoke, including cigarette or cigar smoke
                  ▪ Sudden weather changes


               Physiological Factors


                  ▪ Gastroesophageal reflux disease (GERD)
                  ▪ Hormonal changes
                  ▪ Sinusitis
                  ▪ Stress
                  ▪ Viral upper respiratory infection


               Medications


                  ▪ Acetylsalicylic acid (aspirin)

                  ▪ β-Adrenergic blockers
                  ▪ Nonsteroidal antiinflammatory drugs


               Occupational Exposure Factors


                  ▪ Metal salts
                  ▪ Wood and vegetable dusts
                  ▪ Industrial chemicals and plastics






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