Page 1655 - Saunders Comprehensive Review For NCLEX-RN
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Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Respiratory Medications: Restrictive Airway Disease
               Agents
                  Health Problem: Adult Health: Respiratory: Upper Airway
                  Priority Concepts: Clinical Judgment; Safety
                  Reference: Burchum, Rosenthal (2016), pp. 936-937.


                   588. Answer: 3


                  Rationale: Zafirlukast is a leukotriene receptor antagonist used in the prophylaxis
               and long-term treatment of bronchial asthma. Zafirlukast is used with caution in
               clients with impaired hepatic function. Liver function laboratory tests should be
               performed to obtain a baseline, and the levels should be monitored during
               administration of the medication. It is not necessary to perform the other laboratory
               tests before administration of the medication.
                  Test-Taking Strategy: Eliminate options 2 and 4 first because they are comparable
               or alike, noting that a complete blood count would include a neutrophil count. From
               the remaining options, you would need to know that this medication affects hepatic
               function.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Assessment
                  Content Area: Pharmacology: Respiratory Medications: Restrictive Airway Disease
               Agents
                  Health Problem: Adult Health: Respiratory: Asthma
                  Priority Concepts: Cellular Regulation; Gas Exchange
                  Reference: Hodgson, Kizior (2018), pp. 1246-1247.


                   589. Answer: 2


                  Rationale: Isoniazid is an antitubercular medication. A common side effect of
               isoniazid is peripheral neuritis, manifested by numbness, tingling, and paresthesias
               in the extremities. This can be minimized with pyridoxine (vitamin B ) intake.
                                                                                        6
               Options 1, 3, and 4 are not associated with the information in the question.
                  Test-Taking Strategy: Focus on the information in the question, numbness,
               paresthesias, and tingling in the extremities. Options 3 and 4 would not cause the
               symptoms presented in the question but instead would cause pallor and coolness.
               From the remaining options, you should know that peripheral neuritis is an adverse
               effect of isoniazid, and that these signs and symptoms do not correlate with
               hypercalcemia.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Analysis
                  Content Area: Pharmacology: Respiratory Medications: Tuberculosis Medications
                  Health Problem: Adult Health: Respiratory: Tuberculosis



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