Page 1656 - Saunders Comprehensive Review For NCLEX-RN
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Priority Concepts: Clinical Judgment; Perfusion
                  Reference: Burchum, Rosenthal (2016), p. 1084.


                   590. Answer: 2


                  Rationale: Isoniazid is hepatotoxic, and therefore the client is taught to report
               signs and symptoms of hepatitis immediately, which include yellow skin and sclera.
               For the same reason, alcohol should be avoided during therapy. The client should
               avoid intake of Swiss cheese, fish such as tuna, and foods containing tyramine,
               because they may cause a reaction characterized by redness and itching of the skin,
               flushing, sweating, tachycardia, headache, or lightheadedness. The client can avoid
               developing peripheral neuritis by increasing the intake of pyridoxine (vitamin B )
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               during the course of isoniazid therapy.
                  Test-Taking Strategy: Focus on the subject, client teaching for isoniazid. Because
               alcohol intake is prohibited with the use of many medications, eliminate option 1
               first. Because the client receiving this medication typically is given supplements of
               vitamin B , option 4 is incorrect and is eliminated next. Recalling that the medication
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               is hepatotoxic will direct you to the correct option.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Respiratory Medications: Tuberculosis Medications
                  Health Problem: Adult Health: Respiratory: Tuberculosis
                  Priority Concepts: Client Education; Safety
                  Reference: Skidmore-Roth (2017), pp. 658-659.


                   591. Answer: 3


                  Rationale: Rifampin causes orange-red discoloration of body secretions and will
               stain soft contact lenses permanently. Rifampin should be taken exactly as directed.
               Doses should not be doubled or skipped. The client should not stop therapy until
               directed to do so by a primary health care provider. It is best to administer the
               medication on an empty stomach unless it causes gastrointestinal upset, and then it
               may be taken with food. Antacids, if prescribed, should be taken at least 1 hour
               before the medication.
                  Test-Taking Strategy: Options 2 and 4 are comparable or alike and are inaccurate,
               based on general guidelines for medication administration; the client should not
               double-dose or discontinue medication independently. Eliminate option 1 next
               because of the closed-ended word “always.”
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Respiratory Medications: Tuberculosis Medications
                  Health Problem: Adult Health: Respiratory: Tuberculosis
                  Priority Concepts: Client Education; Safety
                  Reference: Lewis et al. (2017), p. 509.





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