Page 2151 - Saunders Comprehensive Review For NCLEX-RN
P. 2151

2. Carisoprodol
                                                             a. Advise the client to take the medication
                                                                with food to prevent gastrointestinal
                                                                upset.

                                                                    b. Instruct the client to report any

                                                                rash or hypersensitivity to the PHCP.
                                             3. Chlorzoxazone

                                                                    a. Monitor the client for

                                                                hypersensitivity reactions such as
                                                                urticaria, redness or itching, and
                                                                possibly angioedema.
                                                             b. Chlorzoxazone may cause malaise and
                                                                may cause the urine to turn orange or
                                                                red.
                                                             c. Can cause hepatitis and hepatic
                                                                necrosis.
                                             4. Cyclobenzaprine

                                                                    a. Cyclobenzaprine is

                                                                contraindicated in clients who have
                                                                received monoamine oxidase
                                                                inhibitors (MAOIs) within 14 days of
                                                                initiation of cyclobenzaprine therapy
                                                                and in clients with cardiac disorders.
                                                             b. Cyclobenzaprine has significant
                                                                anticholinergic (atropine-like) effects
                                                                and should be used with caution in
                                                                clients with a history of urinary
                                                                retention, angle-closure glaucoma, or
                                                                increased intraocular pressure.
                                                             c. Cyclobenzaprine should be used only
                                                                for short-term therapy (2 to 3 weeks).
                                             5. Dantrolene
                                                             a. Dantrolene acts directly on skeletal
                                                                muscles to relieve spasticity.

                                                                    b. Liver damage is the most

                                                                serious adverse effect.
                                                             c. Liver function values should be
                                                                monitored before the initiation of
                                                                treatment and during treatment.
                                                             d. Dantrolene can cause gastrointestinal
                                                                bleeding, urinary frequency,
                                                                impotence, photosensitivity, rash, and
                                                                muscle weakness.


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