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cardiovascular status, pulse oximetry,
                                                                rate and depth of respirations, urine
                                                                output, bowel sounds, gastric
                                                                secretions and stools for occult blood,
                                                                and temperature and skin changes,
                                                                because the client is at risk for skin
                                                                breakdown due to decreased tissue
                                                                perfusion.
                                D. Systemic Inflammatory Response Syndrome (SIRS)
                                             1. Defined as a systemic inflammatory response that is
                                                characterized by generalized inflammation in organs
                                                separate from the initial affected area; it is a serious
                                                condition and may be caused by a severe bacterial
                                                infection (sepsis), trauma, or pancreatitis.
                                             2. SIRS can also be triggered by a variety of different
                                                mechanisms: mechanical tissue trauma (burns, crush
                                                injuries, surgical procedures); abscess formation;
                                                ischemic or necrotic tissue; microbial invasion;
                                                endotoxin release from invading micro-organisms;
                                                global perfusion deficits including postcardiac
                                                resuscitation or states of shock; and regional
                                                perfusion deficits.
                                E. Multiple Organ Dysfunction Syndrome (MODS)
                                             1. A complication of sepsis; the failure of two or more
                                                organ systems as a result of SIRS, in which
                                                homeostasis cannot be maintained without
                                                intervention.
                                             2. Prognosis is poor once three or more organ systems
                                                fail.
                                             3. Clinical manifestations and management of SIRS and
                                                MODS (Table 69-12).
                                             4. Nursing interventions for SIRS and MODS include
                                                early identification of sepsis; preventing and treating
                                                infections; maintenance of tissue oxygenation;
                                                promoting nutrition to meet metabolic needs; and
                                                support of failing organ systems.



               Table 69-1

               Types of Intravenous Solutions
                                         Solution and Type                                 Uses
                0.9% saline (NS): Isotonic                                       Extracellular fluid deficits in
                                                                                 clients with low serum levels
                                                                                 of sodium or chloride and
                                                                                 metabolic acid–base
                                                                                 imbalances.
                                                                                 Used before or after the
                                                                                 infusion of blood products.
                Ringer’s lactate solution: Isotonic                              Extracellular fluid deficits,



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