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be employed, the nurse must elicit
                                                                from the client the preferred forms of
                                                                spiritual expression and learn when
                                                                they are practiced so that they may be
                                                                integrated into the plan of care.
                    VIII. Pharmacological Interventions
                                A. Nonopioid analgesics
                                             1. Nonsteroidal antiinflammatory drugs (NSAIDs) and
                                                acetylsalicylic acid (aspirin) (Box 10-6)
                                                             a. These medication types are
                                                                contraindicated if the client has gastric
                                                                irritation or ulcer disease or an allergy
                                                                to the medication.
                                                             b. Bleeding is a concern with the use of
                                                                these medication types.
                                                             c. Instruct the client to take oral doses
                                                                with milk or a snack to reduce gastric
                                                                irritation.
                                                             d. NSAIDs can amplify the effects of
                                                                anticoagulants.
                                                             e. Hypoglycemia may result for the client
                                                                taking ibuprofen if the client is
                                                                concurrently taking an oral
                                                                antidiabetic agent.
                                                             f. A high risk of toxicity exists if the client
                                                                is taking ibuprofen concurrently with a
                                                                calcium channel blocker.
                                             2. Acetaminophen
                                                             a. Acetaminophen, commonly known as
                                                                Tylenol, is contraindicated in clients
                                                                with hepatic or renal disease,
                                                                alcoholism, or hypersensitivity.
                                                             b. Assess the client for a history of liver
                                                                dysfunction.
                                                             c. Monitor the client for signs of hepatic
                                                                damage (e.g., nausea and vomiting,
                                                                diarrhea, abdominal pain).
                                                             d. Monitor liver function parameters.
                                                             e. Tell the client that self-medication
                                                                should not continue longer than 10
                                                                days in an adult or 5 days in a child
                                                                because of the risk of hepatotoxicity.
                                                             f. The antidote to acetaminophen is
                                                                acetylcysteine.



                                                                       The major concern with acetaminophen is





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