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f. Hepatosplenomegaly
                                                             g. Meningitis
                                                             h. Disease may spread to all major organs

                                        F. Interventions

                                             1. Pregnant client
                                                             a. Administration of isoniazid,
                                                                pyrazinamide, and rifampin daily for 9
                                                                months (as prescribed); ethambutol is
                                                                added if medication resistance is likely.
                                                             b. Pyridoxine should be administered
                                                                with isoniazid to the pregnant client to
                                                                prevent fetal neurotoxicity caused by
                                                                isoniazid.
                                                             c. Promote breast-feeding only if the client
                                                                is noninfectious.
                                             2. Newborn
                                                             a. Management focuses on preventing
                                                                disease and treating early infection.
                                                             b. Skin testing is performed on the
                                                                newborn at birth, and the newborn
                                                                may be placed on isoniazid therapy;
                                                                the skin test is repeated in 3 to 4
                                                                months, and isoniazid may be stopped
                                                                if the skin test results remain negative.
                                                             c. If the skin test result is positive, the
                                                                newborn should receive isoniazid for
                                                                at least 6 months (as prescribed).
                                                             d. If the mother’s sputum is free of
                                                                organisms, the newborn does not need
                                                                to be isolated from the mother while in
                                                                the hospital.
                    XXIV. Urinary Tract Infection (Acute Cystitis and Acute Pyelonephritis)
                                A. Description: A urinary tract infection can occur during pregnancy
                                   (pregnancy is a predisposing factor). A urinary tract infection can
                                   be either lower urinary tract (cystitis) or upper urinary tract
                                   (pyelonephritis).
                                B. Women may also experience asymptomatic bacteriuria.
                                C. Predisposing conditions
                                             1. History of urinary tract infections
                                             2. Urinary tract anomalies
                                             3. Low socioeconomic status
                                             4. Sexual activity
                                             5. Young age
                                             6. Sickle cell trait
                                             7. Poor hygiene
                                             8. Anemia
                                             9. Diabetes mellitus


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