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Stages of Syphilis

               Primary Stage


                              ▪ Most infectious stage
                              ▪ Appearance of ulcerative, painless lesions produced by spirochetes at
                                point of entry into the body


               Secondary Stage


                              ▪ Highly infectious stage
                              ▪ Appearance of lesions about 6 weeks to 6 months after primary stage;
                                located anywhere on the skin and mucous membranes
                              ▪ Generalized lymphadenopathy


               Tertiary Stage


                              ▪ Entrance of spirochetes into internal organs, causing permanent
                                damage; symptoms occur 10 to 30 years after untreated primary
                                lesion
                              ▪ Invasion of central nervous system, causing meningitis, ataxia,
                                general paresis, and progressive mental deterioration
                              ▪ Deleterious effects on aortic valve and aorta



               Table 22-3

               Risk Factors and Management of Additional Complications During
               Pregnancy




































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