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d i S po S able  pR o C e SS  Solution S  Guide




                         Since this was a dispense to weight operation within a tightly controlled
                         tolerance, the need to separate the support frame and scale from the drum
                         inverter was needed. Figures 5 and 6 show the application of a flexible
                         sleeve with molded sanitary flanges as a method for achieving this need.
                         Fe ATU re S
                         •   Flexible
                         •   Clear

                         •   Sanitary, DN and multi o-ring flange interfaces
                         •   range of Sizes
                                    ®
                         •   ArmorFlex  Family of Films
                         •   Gravity feed                                                          Figure 4
                         •   No capital
                         •   reduced cleaning and disposal

                         Be N e F i TS
                         •   Can be manipulated to overcome bridging, also achieves
                           over 99.5% product discharge
                         •   Operators can see product without exposing product
                                                                                               Figure 5
                         •   interfaces with any vessel interface
                         •   Supports clinical through production scale up
                         •   Assures ruggedness, static dissipation and material of
                           contact compliance
                                                                                                        Figure 6
                         •   No expensive mechanical systems, eliminates validation
                           of mechanical components, simple to use
                         •   Best overall cost of ownership, small footprint
                         •   Supports Green initiatives

                         wHAT   CONT A i NM e NT   L eve L   P r O vi D e D ?
                         Often applied for cGMP containment, however, if a configuration is selected
                                                     ®
                         that interfaces with a DoverPac  multiple o-ring canister as in Figure 3,
                         containment in the nanogram range can be achieved.

                         wH y  US e  TH i S   O ver  OTH er  T e CHNOLOG ie S ?
                         •   reduced cost of ownership
                         •   eliminates cleaning and cleaning validation
                         •   eliminates waste treatment of cleaning solutions
                         •   Best product recovery

                         •   visual access to drug product being manufactured
                         •   Liner can be manipulated to overcome bridging





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