Page 7 - Black Pepper

dōTERRA

Black Pepper Study

Black Pepper is a unique essential oil. With a chemical makeup including
rich concentrations of caryophyllene and limonene, its breadth of benefits

extends well past its ability to enhance the flavor of various foods. It has
been extensively studied for its benefits when consumed, including

previous research examining its ability to promote healthy circulation, assist

with digestion, and provide powerful antioxidant support, but there has
been limited investigation of its biological activities in human cells.* A
recently published study conducted by dōTERRA scientists suggests that

CPTG® Black Pepper may also be effective in supporting proper

inflammatory and healthy metabolic processes.

Using the BioMAP® HDF3CGF system, which doTERRA scientists have used

previously to examine the activity of several CPTG essential oils in human
dermal fibroblasts, Black Pepper was analyzed for its influence on the levels

of 17 important protein biomarkers and regulation of global gene

expression1. Similar to previous research that examined constituents
caryophyllene and limonene in isolation, Black Pepper was found to have

an inhibitory effect on collagen production, suggesting it may have
potential to aid in a variety of healthy inflammatory processes.

Furthermore, Black Pepper exhibited robust modulation of signaling
pathways involved in metabolism and cellular health. While further research

needs to be conducted, these findings suggest that Black Pepper essential
oil may have a variety of uses in topical application models that have yet to

be explored, including tissue remodeling.

Once again, doTERRA continues to be at the forefront of essential oil
science, providing the first peer-reviewed study to evaluate the biological

activity of Black Pepper essential oil in human skin cells. Expect future
research to provide additional information on how the purest and most

potent CPTG Black Pepper essential oil can be used to promote lifelong
health and vitality.