Page 1190 - Basic _ Clinical Pharmacology ( PDFDrive )

Asplenia and other at-risk conditions Travelers to hepatitis A endemic areas Men who have sex with men (MSM) Injection or noninjection illicit drug users Chronic liver disease or clotting factor disorders Persons with occupational risk for infection Persons living in, or relocating to, endemic areas Household and sexual contacts of individuals with acute hepatitis A (with additional gamma globulin in select patients) Unvaccinated persons who anticipate close personal contact with an international

Indications For all children For all children 1. 2. 1. 2. 3. 4. 5. 6. 7. For all children 8. 9. For all infants 1. 2. 3. 4. 5. 6. 7. hepatitis B 1. 2. 3. All adults >18 years 1. 2.

Booster 2 None Not recommended At 6–12 months for long-term immunity Not routinely recommended None Yearly with current vaccine
Materials commonly used for active immunization in the United States. 1

Primary Immunization See Table A–2 One dose (see Table A–2 for childhood schedule) One dose (see Table A–2 for childhood schedule) (administer at least 2–4 weeks before travel to endemic areas) Three doses at 0, 1, and 6 months (see Table A–2 for childhood schedule) Three doses at 0, 4–8, and 24 weeks One dose (Children <9 years who are receiving influenza vaccine for the first time should receive two doses administered at least 4 weeks apart.)

Route of Administration Intramuscular Intramuscular Intramuscular Intramuscular (subcutaneous injection is acceptable in individuals with bleeding disorders) Intramuscular Intramuscular; an intradermal vaccine is avail- able for adults aged 18–64 years; a high-dose for- mulation is an option for adults ≥65 years

Type of Agent Toxoids and inactivated bacterial components Bacterial polysaccharide conjugated to protein Inactivated virus Inactive viral antigen, recombinant Virus-like particles of the major capsid protein Inactivated virus or viral components

TABLE A–1 Vaccine Diphtheria tetanus acellular pertussis (DTaP) Haemophilus influenzae type b conjugate (Hib) 3 Hepatitis A Hepatitis B Human papillomavirus (HPV) 4 Influenza, inactivated

1176