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274 SECTION III Cardiovascular-Renal Drugs
PREP AR A TIONS A V AIL ABLE
GENERIC NAME AVAILABLE AS GENERIC NAME AVAILABLE AS
Acetazolamide Generic, Diamox Hydrochlorothiazide Generic, Esidrix, Hydro-DIURIL,
Amiloride Generic, Midamor, combination combination drugs *
drugs * Hydroflumethiazide Generic, Saluron
Bendroflumethiazide Naturetin, combination drugs * Indapamide Generic, Lozol
Brinzolamide (for ocular Azopt Mannitol Generic, Osmitrol
conditions) Methazolamide (for ocular Generic, Neptazane
Bumetanide Generic, Bumex conditions)
Canagliflozin Invokana Methyclothiazide Generic, Aquatensen, Enduron
Dapagliflozin Farxiga Metolazone Generic, Mykrox, Zaroxolyn
Chlorothiazide Generic, Diuril (Note: Bioavailability of Mykrox is
Chlorthalidone Generic, Hygroton, Thalitone, greater than that of Zaroxolyn)
combination drugs * Nesiritide Natrecor
Conivaptan Vaprisol Polythiazide Renese, combination drugs *
Demeclocycline Generic, Declomycin Quinethazone Hydromox
Dichlorphenamide Diclofenamide Spironolactone Generic, Aldactone, combination
*
Dorzolamide (for ocular Generic, Trusopt drugs
conditions) Tolvaptan Samsca
Eplerenone Inspra Torsemide Generic, Demadex
Ethacrynic acid Edecrin Triamterene Dyrenium
Furosemide Generic, Lasix, others Trichlormethiazide Generic, Diurese, Naqua, others
*
Combination drugs: see Table 15–6.
REFERENCES Hill JA, Yancy CW, Abraham WT: Beyond diuretics: Management of volume
overload in acute heart failure syndromes. Am J Med 2006;119:S37.
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research
Group: Major outcomes in high-risk hypertensive patients randomized to Kaplan NM: The place of diuretics in preventing cardiovascular events. J Hum
angiotensin-converting enzyme inhibitor or calcium channel blocker vs Hypertens 2004;18:S29.
diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Kim G-H et al: Antidiuretic effect of hydrochlorothiazide in lithium-induced neph-
Heart Attack Trial (ALLHAT). JAMA 2002;288:2981. rogenic diabetes insipidus is associated with upregulation of aquaporin-2,
Bakris GL et al: Effect of finerenone on albuminuria in patients with diabetic Na-Cl co-transporter, and epithelial sodium channel. J Am Soc Nephrol
nephropathy. JAMA 2015;314:884. 2004;15:2836.
Berl T et al: Oral tolvaptan is safe and effective in chronic hyponatremia. J Am Soc Klein JD, Sands JM: Urea transport and clinical potential of urearetics. Curr Opin
Nephrol 2010;21:705. Nephrol Hypertens 2016;25:1.
Bokrantz T et al: Thiazide diuretics and fracture-risk among hypertensive patients. Lee C, Burnett J: Natriuretic peptides and therapeutic applications. Heart Fail
Results from the Swedish primary care cardiovascular database (SPCCD). Rev 2007;12:131.
J Hypertens 2015;33:e94. Matsue Y et al: Clinical effectiveness of tolvaptan in patients with acute heart failure
Brater DC: Mechanism of action of diuretics. UpToDate, 2013. http://www. and renal dysfunction: AQUAMARINE study. J Card Fail 2016;22:423.
+
uptodate.com. Na KY et al: Upregulation of Na transporter abundance in response to chronic
Brenner BM (editor): Brenner & Rector’s The Kidney, 8th ed. Saunders, 2008. thiazide or loop diuretic treatment in rats. Am J Physiol 2003;284:F133.
Cefalu WT et al: Efficacy and safety of canagliflozin versus glimepiride in patients Nariai T et al: DSR-71167, a novel mineralocorticoid receptor antagonist with
with type 2 diabetes inadequately controlled with metformin (CANTATA- carbonic anhydrase inhibitory activity, separates urinary sodium excretion
SU): 52 week results from a randomized, double-blind, phase 3 non- and serum potassium elevation in rats. Pharmacol Exp Ther 2015;354:2.
2+
2+
inferiority trial. Lancet 2014;382:941. Nijenhuis T et al: Enhanced passive Ca reabsorption and reduced Mg channel
Cooper BE: Diuresis in renal failure: Treat the patient, not the urine output. Crit abundance explains thiazide-induced hypocalciuria and hypomagnesemia.
Care Med 2009;37:761. J Clin Invest 2005;115:1651.
Costello-Boerrigter LC, Boerrigter G, Burnett JC Jr: Revisiting salt and water Olde Engberink RHG et al: Effects of thiazide-type and thiazide-like diuretics on
retention: New diuretics, aquaretics, and natriuretics. Med Clin North Am cardiovascular events and mortality. Hypertension 2015;65:1033.
2003;87:475. Schnermann J, Huang Y, Mizel D: Fluid reabsorption in proximal convoluted
Ernst ME, Moser M: Use of diuretics in patients with hypertension. N Engl J Med tubules of mice with gene deletions of claudin-2 and/or aquaporin1. Am J
2009;361:2153. Physiol Renal Physiol 2013;305:F1352.
Forssmann W-G, Meyer M, Forsmann K: The renal urodilatin system: Clinical Shargorodsky M et al: Treatment of hypertension with thiazides: benefit or
implications. Cardiovasc Res 2001;51(3):450. damage—Effect of low- and high-dose thiazide diuretics on arterial elasticity
and metabolic parameters in hypertensive patients with and without glucose
Ginés P, Schrier RW: Renal failure in cirrhosis. N Engl J Med 2009;361:1279. intolerance. J Cardiometab Syndr 2007;2:16.
Hao C-M, Breyer MD: Physiological regulation of prostaglandins in the kidney. Shlipak MG, Massie BM: The clinical challenge of cardiorenal syndrome. Circula-
Annu Rev Physiol 2008;70:357. tion 2004;110:1514.
Hays RM: Vasopressin antagonists: Progress and promise. N Engl J Med 2006; Sica DA, Gehr TWB: Diuretic use in stage 5 chronic kidney disease and end-stage
355:146. renal disease. Curr Opin Nephrol Hypertens 2003;12:483.