Page 368 - Atlas of Histology with Functional Correlations
P. 368

neurotransmitters

                   Anterograde  transport  is  via  microtubules  in  axons  to  axon  terminals  or
                   synapses
                   Retrograde transport is via microtubules from axon terminals and dendrites to
                   neurons
                   Axonal transport requires microtubule-associated motor proteins kinesin and

                   dynein


               SUPPORTIVE                              CELLS                    IN             CNS:


               NEUROGLIA






                   Supportive, nonneural cells that surround neurons, axons, and dendrites
                   Small cells that do not conduct impulses
                   Ten times more numerous than neurons
                   Four types: astrocytes, oligodendrocytes, microglia, and ependymal cells



               Astrocytes



                   Are the largest and most numerous in gray matter
                   Consist of two types: fibrous astrocytes and protoplasmic astrocytes

                   Both  types  abut  on  capillaries  and  form  tight  junctions  and  blood–brain
                   barrier
                   Form glial limiting membrane that surrounds the brain and the spinal cord
                   Support metabolic exchange and contribute to the energy metabolism of the

                   CNS
                   Control  the  chemical  environment  around  neurons  by  clearing  increased
                   potassium ions and neurotransmitters such as glutamate
                   Gap junctions form structural syncytia in the CNS and the communication

                   network in the brain
                   In response to injury, cells divide and form scar tissue


               Oligodendrocytes




                   Surround and myelinate numerous axons at one time, in contrast to Schwann
                   cells
                   Do not surround multiple and unmyelinated axons



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