Page 579 - Atlas of Histology with Functional Correlations

intrinsic factor

Gastric intrinsic factor is essential for absorption of vitamin B12 and for
erythropoiesis
Chief cells produce pepsinogen that is converted to pepsin in acidic
environment
Enteroendocrine cells secrete a variety of polypeptides and proteins for

digestive functions
Mucus-secreting stomach cells change to intestinal epithelium in the
duodenum

Review Questions

In the following multiple choice questions, choose the letter corresponding to the

one best answer.

1. What induces pepsinogen to convert into pepsin?

A. Mucus secretion by luminal cells

B. Gastric intrinsic factor release

C. Acidic environment containing hydrochloric acid

D. Gastrin secretion

E. Bicarbonate or neutral content of chyme

2. What role does the gastric intrinsic factor play in the digestive process?

A. It increases digestive tract motility and digestion of its contents.

B. It neutralizes pepsinogen and pepsin.

C. It stimulates the production of hydrochloric acid.

D. It is necessary for absorption of vitamin B12 from the small intestine.

E. It activates the enteroendocrine cells to produce hormones.

3. Zymogenic or chief cells of the gastric glands produce:

A. gastric intrinsic factor.

B. pepsinogen.

C. pepsin.

D. hydrochloric acid.

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