Page 49 - Book of Abstracts

th
8 Biannual Conference on Chemistry - CHEM 08

Phytochemical Constituents and Radical Scavenging (Anti-

oxidant) Efficacies of Leaf Ficus Sycomorus Linn Moraceae

Fanna I. Abdulrahaman ,Mustapha A. Tijjani and Usman B.
1
1
Shamaki
2
1 Department of Chemistry, Faculty of Science, University of Maiduguri,
P.M.B 1069, Maiduguri, Borno State, Nigeria, Department of Veterinary
2
Pharmacology and Toxicology, Faculty of Veterinary Medicine,
University of Maiduguri, Borno state.
Email: mustaphatijjani22@yahoo.com

ABSTRACT

This study was aimed at evaluating phytochemical constituents of Ficus
sycomorus and anti-oxidant (radical scavenging) properties. Theleaves
were extracted with 95% methanol with soxhlet extractor and the crude
extract was partitioned with solvents of graded polarities and purified in
column chromatography and PTLC which results to isolation of two sub-
fractions (Compounds) C1 and C3. Phytochemical screening of the
extracts revealed the presence of many pharmacologically active
secondary metabolites. .UVis spectrum of C1 revealed an absorption ƛmax
at 650.60 nm and 503.00 nm which are similar to ƛmax of alkaloids. Also‚
the UVis spectrum of C3 revealed absorption ƛmax at 657.20 nm‚ 602.80 nm
and 503.20 nm which are also similar to ƛmax of alkaloids. FTIR spectra
revealed bands at 3333.1 cm (N-H stretch in secondary amine)‚ 1790 cm -
-1
1 (C=O stretch of ring carbonyl), 1427.37 cm (C=C stretch of aromatic
-1
compounds) and 2962.76 (C-H stretch methyl group). GCMS analysis of
C1 and C3 when compared with NIST library revealed many compounds
such as 4-(3‚4-dimethoxyphenyl)-5-methyl-2-thiazolamine, O-(2-
methylpropyl)-Hydroxylamine and cyclobarbital. The antioxidant
evaluation showed that the partitioned portions of n-butanol,n-hexane,
ethyl acetate and aqueous extract indicates antioxidant activities at
various concentrations, however methanol extract showed the highness
percentage inhibitions (98.25 at 10ug/ml 97.40 at 20µg/ml 96.94 at 30µg/ml
96.63 at 40µg/ml and 97.10 at 50µg) .Thus Ficus sycomorus is a promised
plant that has radical scavenging activities as indicated by from the study.

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