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2017 CAO CONGRESS POSTER ABSTRACTS

of 1 or 0 depending on the presence or absence, respectively, of RPE disruption (melanin migration or aggregation),
drusen and/or geographic atrophy in one or both eyes.

The results were compared to the DA rod intercept in minutes for the short duration (6.5 minutes) screening
on the same day for each eye. 65.6% of the patients were female and the mean age was 58.5 ± 9.2 years. The
sensitivity and specificity of the MSI images relative to DA results were calculated for the highest rod intercept
of each patient.

R E S U LT S
DA was the standard to which MSI was compared. 13 patients were true positives and 1 was a false negative for
AMD. There were 9 true negatives, considered healthy normal by both tests and 9 false positives found with MSI.
The sensitivity of MSI for diagnosing AMD was 92.9% however it was only 50.0% specific.

CONCLUSION
MSI is highly sensitive for diagnosing AMD as compared to DA, although it is not specific for AMD, identifying
normal drusen of aging and RPE disruption of other origins. This suggests that MSI is an excellent screening tool
for ocular pathology and can drive more patients toward DA for a definitive diagnosis of AMD.

CONFLICT OF INTEREST DISCLOSURE
Dr. Zimmer is the Clinical Affairs and Research Manager at Annidis Corporation.

orders@whiteop.ca Tel: 1-800-661-1562 41
www.whiteop.ca Fax: 1-800-661-9175

CANADIAN JOURNAL of OPTOMETRY | REVUE CANADIENNE D’OPTOMÉTRIE VOL. 79 NO. 2