Page 82 - Pharmaceutical Organic Chemmistry-3 (Theoritical book) 24-25
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Clinical Pharmacy PharmD - 2024/2025 Level 2 Pharmaceutical Organic Chemistry-3 (PC 305)
Other Biologically Important Sugars
Monosaccharides in which an OH group has been replaced by H are known as
deoxy sugars. The most important deoxy sugar, because it occurs in DNA, is
deoxyribose. Other deoxy sugars that occur widely in polysaccharides are L-
rhamnose and L-fucose.
Sugars That Contain Nitrogen
a) Glycosylamines
A sugar in which an amino group replaces the anomeric OH.
Examples are β-D-glucopyranosylamine and adenosine.
b) Amino Sugars
A sugar in which an amino group replaces a non-anomeric OH group.
D-Glucosamine is an example of an amino sugar.
In many instances the amino group is acetylated as in N-acetyl-D-glucosamine.
N-Acetylmuramic acid is an important component of bacterial cell walls.