Page 8 - Eureka! Fall 2005
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Faculty news  ALIEN invasion                                                                                                                                  Demystifying alternative                                                  Faculty news


                                                                                                                                                                   medicine: Seeking the truth behind
                                                                                                                                                                                     echinacea and scorpion venom
                  he aliens have landed, and they’re
                                                                                   highly invasive plants are so chemi-
                                                 vine, which came to North America
                                                 from Ukraine and Russia, says Cap-
               ttaking North America by storm.
                                                                                   cally unique that no herbivores can
                 Alien plants brought in from other
               continents are infiltrating North
                                                 hold on many Toronto-area landscapes
                                                                                   attack them. In the case of the dog-
               American landscapes at an alarm-  puccino. The plant now has a strangle-  eat them and no native fungi can                                          Centre for Disease Control.         “I think there is some truth to about
                                                                                   strangling vine, they proved this to be
                                                 as well as upstate New York.
               ing rate. Once their growth patterns   So the Carleton biologist began   true. The plant’s chemicals are com-                                         “Our theory is that if echinacea,   25 percent of the myths (concerning
               spiral out of control, these resilient   studying this pest of a plant. And the   pletely foreign to North America.                                 for example, is truly effective, it   homeopathic remedies),” Golshani says.
               invaders threaten the survival of local   more she and her colleagues studied   The next step of the research is to                                 must have some sort of activity with   “But I think the most important thing is
               species and create a huge expense for   it, the more they realized it was toxic   grow natural herbivores such as the                               certain gene products and pathways   for scientists to keep their mind open.”
               wildlife authorities, says Naomi Cap-  to everything. At the heart of its toxic-  American locust and determine its pref-  Ashkan Golshani, Biology professor  within the cell,” he says.   Getting to the bottom of those myths,
               puccino, a professor of Biology who is   ity is an active compound that actu-  erences when faced with plants that are                                While echinacea has long been   however, can be very time-consuming
               conducting cutting-edge research on   ally deters herbivores from eating the   either highly invasive or non-invasive.   or years, the healing powers of   favoured by Canadian Aboriginal Peo-  if it’s done manually. Recently, some
               ways to identify and eradicate some   plant. Biology professor Myron Smith   Helping Cappucino with this stage   F homeopathic medicines have been   ples for its anti-fungal properties, Gol-  scientists have begun using a new robot
               of the worst culprits.            and Thor Arnason, a phytochemist   is Tania Jogesh, a fourth-year honours       steeped in mystery.               shani wants to find out how it actually   specifically designed to test the various
                 Often there are no natural patho-  from the University of Ottawa, also   student and insect enthusiast. The       While there may be an abundance   stops the growth of yeast. This means   combinations of gene-deletions with the
               gens or herbivores to keep the growth   discovered the plant has some really   insect experiment comprises the bulk   of anecdotal evidence supporting   deleting specific genes in thousands of   homeopathic compound in question.
               of alien populations in check. Of par-  strong anti-fungal properties.   of Jogesh’s thesis.                      alternative remedies such as echi-  yeast strains and applying echanesia   “All of a sudden, we have the com-
               ticular concern in the last few years   Along with Arnason, Cappucino has   “I love insects,” she says from the   nacea and scorpion venom, there is   in their absence. In doing so, scientists   puter automation power to do this
               is the swallow-wort or dog-strangling   addressed the question of whether   Nesbitt greenhouses which contain     very little empirical evidence to prove   could theoretically see if the healing   type of work, such as crossing 4,000
                                                                                   fully-grown grasshoppers that were            these treatments are directly respon-  affect of echanesia and function of   strains of yeast with one another,”
                                                                                   recently shipped from the U.S.                sible for someone’s recovery.     each deleted gene are related.    says Golshani. “There are so many
                                                                                     By determining the plant prefer-              But if biologists are able to exam-  The same concept could be applied   questions we can now get answers to.”
                                                                                   ence of these insects, the study could        ine some of these natural compounds   to scorpion venom, which is believed   Golshani intends to seek new re-
                                                                                   offer wildlife authorities new insight        at the molecular level, they may get   by some groups to have anti-cancer   search funding so he can add this new
                                                                                   into which foreign plants are menac-          the definitive proof they need to turn   properties. Especially popular in Cuba,   technology to his lab in the Nesbitt
                                                                                   ing enough to warrant a bio-control           homeopathic remedies into cutting-  this natural compound is now the fo-  Building. The lab, which is designed
                                                                                   program, adds Jogesh. These decisions         edge designer drugs, explains Ashkan   cus of researchers in Alabama who are   to create new antibiotics, recently
                                                                                   are critical since such a tracking and        Golshani, a Biology professor who is   trying to determine if it can be used to   received $177,840 in funding from the
                                                                                   quarantine program can cost roughly           the director of Carleton’s Genomics   treat primary brain tumors.   Canada Foundation for Innovation.
                                                                                   $300,000 per species, says Cappuccino.
                                                                                     “Hopefully, our research will help
                                                                                   people in their decision-making,” she         Cyber-crime meets its match
                                                                                   says. “If you can somehow predict
                                                                                   which plants are going to cause the            n a bid to gain an advantage over cy-  for Carleton because the university
                                                                                   worst problem before they spread all         I ber-criminals, Carleton has co-found-  houses one of the largest digital
                                                                                   across North America, then you can            ed a unique Internet security forum.   security research groups in Canada,
                                                                                   get at these plants while they’re still         The Forum for Information Secu-  explains Paul Van Oorschot, a profes-
                                                                                   manageable. The chemistry and the             rity Innovation in Canada (FISIC)   sor in Carleton’s School of Computer
                                                                                   herbivore damage might be one clue            promises to increase public aware-  Science and Canada Research Chair
                                                                                   as to whether or not the plant will           ness about potential gaps in Internet   in Network and Software Security.
                                                                                   become a really bad one.”                     security and offer new ways to stop   Expertise in the School of Computer
                                                                                                                                 cyber-criminals.                  Science includes intrusion detection,
                                                                                                                                   Teaming up with Carleton to ad-  authentication, Internet routing se-
                                                                                                                                                                   curity, software protection, applica-
                                                                                      !    Fast fact...                          dress these pressing issues include   tion security, and wireless security.   Paul Van Oorschot, canada Research chair in
                                                                                                                                 Bell Security Solutions Inc., Bell Uni-
                                                                                                                                                                                                     Network and software security.
                                                                                                                                                                     Van Oorschot expects banks to join
                                                                                                                                 versity Labs, and the federally-funded
                                                                                     Each year, the U.s. Fish and wildlife       Mathematics of Information Technol-  FISIC since they have a common in-  the eventual goal is to have intercon-
                                                                                     service spends Us$10 million dollars        ogy and Complex Systems based at   terest in protecting online customers.   nected pockets or clusters of exper-
                                                                                     on controlling exotic plant species. this   Simon Fraser University, B.C.     He also anticipates more academic   tise across the country that can easily
                                                                                     doesn’t include the billions in annual        Together, they will work on FISIC’s   partners to crop up across the coun-  collaborate on digital security issues
                                                                                     damages to the agriculture and forestry     debut project: to investigate the tech-  try. Thus far, Dalhousie University   and work toward common goals.
                                                                                     industries, as well as range lands and      nologies and processes used to fight   and the University of Calgary have   Other founding partners of FISIC
                                                                                     roadways. Meanwhile, 42 percent of                                            expressed interest.
                                                                                     America’s endangered and threatened         email abuse, such as spamming and                                   include the Canadian Advanced Tech-
                                                                                     species have declined as a result of        spoofing, as well as expensive denial-  “Our intention is to get like-minded   nology Alliance and Communications
                                                                                     encroaching exotic plants and animals.      of-service (DoS) attacks that can deny   companies, universities, and ap-  and Information Technology Ontario,
               Biology professor Naomi cappuccino holds one of several American grasshoppers that will be used in her            businesses millions of dollars.   propriate government departments   an Ontario Centre of Excellence. Visit
               ongoing research on alien plants                                      Source: National Park Service                 FISIC’s debut project is a good fit   together,” Van Oorschot says, adding   FISIC at fisic.ca.

               8 EUREKA!     FALL 2005                                                                                                                                                                   eur eka.carleton.ca 9
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