Page 1 - Volume XIII- Hospital Newsletter
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MiCare E-Newsletter                                                                           Vol XIII



























                                                                                TUBERCULOSIS






    Tuberculosis (TB) is a notable disease globally           (coughing  up of blood), fatigue, appetite and
    and in Malaysia. In 2018, the World Health Orga-          weight loss.  The symptoms of  Extrapulmonary
    nization (WHO)  estimated 10 million global TB            Tuberculosis  vary according  to the organs
    cases. The local incidences of TB in 2018 were            involved  eg. lymph nodes may have enlarged
    92/100,000  cases (27600  cases), majority  of            neck glands. TB Meningitis (brain) may present
    patients were between 21-60 years age (69.5%)             with intermittent or  persistent headaches for  a
    and gender  predominance  (65%) were male.                few weeks followed with behavioral changes and
    The states in Malaysia that recorded the highest          may progress into a coma over a few weeks.
    cases were Sabah and Selangor. TB transmis-               Pleural Tuberculosis may present with shortness
    sion risks include close TB contacts which post           of breath from days to weeks, chest pain, inter-
    4x the risk and diabetics susceptible to  3x the          mittent fever, fatigue and lethargy.
    risk.  Other contributing risk factors  include:
    people  with existing chronic lung diseases,              The diagnosis of TB is made by the presence of
    kidney diseases, cancer, malnutrition, substance          the above symptoms; chest X ray and confirma-
    abuse, smokers and alcoholics.                            tion of the presence of Mycobacterium Tubeculo-
                                                              sis in the sputum or any other tissue; and fluid (in
    TB is an infectious disease caused by the bacte-          Extrapulmonary Tuberculosis). TB is a treatable
    ria Mycobacterium  Tuberculosis.  There are 2             disease  with anti  TB medications.  The most
    types of TB: Pulmonary Tuberculosis (PTB) and             common medications used are Etahmbutol, Iso-
    Extrapulmonary  Tuberculosis  (EPTB). PTB                 niazid,  Rifampicin  and Pyrizinamide.  These
    affects the lungs and is the most common type of          medications may  have side effects  which
    TB. Extrapulmonary Tuberculosis is an infection           include  nausea, vomiting,  numbness  of
    which affects any organ outside the lungs such            hands and feet, visual disturbances and
    as the common pleura (lung covering) and lymph            occasionally  liver  toxicity.    The  duration of
    nodes. Extrapulmonary  Tuberculosis  may also             treatment for PTB/ EPTB is usually 6 months (it
    affect muscles, bones, brain, abdomen and geni-           can be extended up to 12 months depending on
    tourinary system.                                         situations). The regime consist on a daily 4 drug
                                                              regime for 2 months which is called the intensive
    Pulmonary  Tuberculosis  symptoms include                 phase followed by a daily 2 drug regime for the
    chronic productive cough (>2 weeks), chest pain,          remainder of the course which is called the main-
    intermittent fever, night sweats, haemoptysis             tenance regime. The combination of therapeutics


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