Page 10 - Cleaning and sanitation in GMP

GMP Training – Cleaning and Sanitation in GMP Areas by www.gmpsop.com

Disinfectant
Proper use results in 100% kill of vegetative
DISINFACTANT bacteria, target viruses and target fungi. Pre-
cleaning may or may not be required, but it is
considered a pre-requisite.

Sterilant

Proper use results in 100% kill of all micro-
STERILANT organisms, including bacterial spores. Pre-
cleaning is always required in order to reduce
bioload and dirt.

Sporicide
SPORICIDE Proper use results in 100% kill of all bacterial
spores.

GOOD TO KNOW - WHAT DOES PROPER USE MEAN?

Proper use means using the agent under specific conditions to ensure they are
optimally effective. The conditions of use are described in written procedures.

GOOD TO KNOW - "STERILISATION" VS. "SANITATION"

Sterilization means the total elimination of any living organisms, usually by

heat or chemical means, of any living organisms.

Sanitation means the reduction in microbial load (the bio burden) by chemical
means. The end result of sanitation does not guarantee the complete absence
of micro-organisms.

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