Page 11 - Cleaning and sanitation in GMP

GMP Training – Cleaning and Sanitation in GMP Areas by www.gmpsop.com

The majority of chemical and physical agents in use will clean and sanitize
and/or disinfect but not sterilize.

GOOD TO KNOW - COMMON SANITIZERS

70% v/v alcohol (for surfaces)

Quaternary ammonium compounds (QUATs)

Phenolics

Sporicides (for killing spores)

Chlorines (such as hypochlorite)

Hydrogen peroxide/peracetic acids

Sodium hydroxide (cleaning & partial sanitizing)

You should be familiar with your company agents and only use approved
agents in the nominated strengths.

GMP rules and cleaning

The GMP rules are very explicit regarding the requirement to clean and sanitize

equipment and the manufacturing facility.

Since most residues cannot be seen nor reliably tested for, the company's
standard procedures and cleaning records are relied upon as evidence of
cleaning.

Copyright©www.gmpsop.com. All rights reserved
Unauthorized copying, publishing, transmission and distribution of any part of the content by electronic means are strictly prohibited.
Page 11 of 42