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31/10/2025, 23:40 Community Pharmacy Practice - Course Materials
Adverse Drug Reactions
Definition:
"is a response to a drug that is noxious and unintended and which occurs at doses normally
used in humans for the prophylaxis, diagnosis or therapy of disease or for the modification of
a physiological function. " WHO, 1970 Since 2012"
ADR also could result from medication errors and uses outside the terms of the marketing
authorisation, including the misuse and abuse of the medicinal product.
TERMS..any difference? ADVERSE EVENT "are not necessarily
related to drug therapy but, in terms of a
Adverse reactions=Adverse effect medicine's use, they describe any adverse
Side effect=minor, predictable ADRs. (could effect that occurred during drug therapy "
be beneficial)
The Relationship Among ME, ADEs & ADRs
Medication errors are more common than adverse drug events, but result in harm less than 1% of the time.
About 25% of adverse drug events are due to medication errors
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