Page 39 - Community pharmcy practice E-book 2025

31/10/2025, 23:40 Community Pharmacy Practice - Course Materials

Anaphylactic shock

It is an extremely serious allergic drug reaction that usually occurs shortly after the
administration of a drug to which the individual is sensitive.
Anaphylactic shock can be fatal if the symptoms are not identified and treated immediately.
Treatment is to raise the blood pressure, improve breathing, restore cardiac function, and treat
other symptoms as they occur

More subtypes of ADR

It includes Categories for ADRs caused by

Long-term use of a drug,
Drug – drug interactions, or
Overdose
Carcinogenicity or teratogenicity.

ADRs affect the public's confidence in medicines

Following the withdrawal of rofecoxib in 2004, the debate over cyclooxygenase 2 (COX-2)
inhibitors made repeated national headlines.
ketamine abuse,
Muscle adverse effects of statins,
Cardiac ADRs with NSAIDs,
Fatalities associated with tramadol, and the MMR vaccine debate, which continues to have real
impact on public health.

Information resources on ADRs

BNF
Martindale
Meyler's Side Effects of Drugs
Stockley's Drug Interactions

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