Page 42 - Community pharmcy practice E-book 2025
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31/10/2025, 23:40 Community Pharmacy Practice - Course Materials
LONG-TERM DRUG EFFECTS….read and know the
difference
Drug abuse
Drug misuse
Drug tolerance
Drug resistance
Drug dependence
Drug withdrawal
Genotoxicity
Mutagenicity
Tumorigenicity
Assignment 3
FIND THE DIFFERENCE IN MEANING?
How to prevent some ADEs??
Dosage reduction in case of tachcardia (Atenolol) or diarrhea with others..
Discontinue if hypotension(Labelol or many coadministered antihypertensives)
Monitoring if bleeding(INR with warfarin)
Change drug (paracetamol) if Gastritis with NSAIDs
Management of ADR
Modifying dose of drug
Use of alternative drug
Can consider prophylactic regimen (if seen to be effective)
Patient /physician education
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